Probing the active site of serine hydrolase enzymes by molecular dynamics of their phosphonate ester adducts

被引:0
|
作者
Kovach, IM [1 ]
Bencsura, A [1 ]
Enyedy, IJ [1 ]
机构
[1] Catholic Univ Amer, Dept Chem, Washington, DC 20064 USA
来源
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1998年 / 215卷
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
195-COMP
引用
收藏
页码:U557 / U558
页数:2
相关论文
共 50 条
  • [31] Active site modeling in copper azurin molecular dynamics simulations
    Rizzuti, B
    Swart, M
    Sportelli, L
    Guzzi, R
    JOURNAL OF MOLECULAR MODELING, 2004, 10 (01) : 25 - 31
  • [32] Cold-active enzymes studied by comparative molecular dynamics simulation
    Spiwok, Vojtech
    Lipovova, Petra
    Skalova, Tereza
    Duskova, Jarmila
    Dohnalek, Jan
    Hasek, Jindrich
    Russell, Nicholas J.
    Kralova, Blanka
    JOURNAL OF MOLECULAR MODELING, 2007, 13 (04) : 485 - 497
  • [33] Cold-active enzymes studied by comparative molecular dynamics simulation
    Vojtěch Spiwok
    Petra Lipovová
    Tereza Skálová
    Jarmila Dušková
    Jan Dohnálek
    Jindřich Hašek
    Nicholas J. Russell
    Blanka Králová
    Journal of Molecular Modeling, 2007, 13 : 485 - 497
  • [34] A MOLECULAR-MODEL FOR THE ACTIVE-SITE OF S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE
    YEH, JC
    BORCHARDT, RT
    VEDANI, A
    JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 1991, 5 (03) : 213 - 234
  • [35] Computational active site analysis of molecular pathways to improve functional classification of enzymes
    Ozyurt, A. Sinem
    Selby, Thomas L.
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2008, 72 (01) : 184 - 196
  • [36] Molecular simulations of the influence of crowders on enzymes: From domain motion to the active site
    Pluharova, Eva
    Timr, Stepan
    Vokacova, Zuzana Sochorova
    Nori, Human A.
    Slade, Kristin M.
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 14A - 14A
  • [37] Transient fluorescent shifts elucidate enzymes active site dynamics-function relationships
    Amaro, M.
    Sykora, J.
    Hof, M.
    Stepankova, V.
    Brezovsky, J.
    Prokop, Z.
    Damborsky, J.
    Chaloupkova, R.
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2013, 42 : S173 - S173
  • [38] Active-site electronic properties and conformational dynamics of pet-degrading enzymes
    Poleto, Marcelo D.
    Lemkul, Justin A.
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 446A - 446A
  • [39] Human lysosomal acid lipase cholesteryl ester hydrolase and human gastric lipase: identification of the catalytically active serine, aspartic acid, and histidine residues
    Lohse, P
    ChahrokhZadeh, S
    Lohse, P
    Seidel, D
    JOURNAL OF LIPID RESEARCH, 1997, 38 (05) : 892 - 903
  • [40] Active-site-dependent elimination of 4-nitrophenol from 4-nitrophenyl alylphosphonyl serine protease adducts
    Kovach, IM
    Enyedy, EJ
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (02) : 258 - 263