Probiotic Bile Salt Hydrolase: Current Developments and Perspectives

被引：115

作者：

Patel, Anil K. ^{[2
]}

Singhania, Reeta R. ^{[1
]}

Pandey, Ashok ^{[1
]}

Chincholkar, Sudhir B. ^{[2
]}

机构：

[1] CSIR, Div Biotechnol, Natl Inst Interdisciplinary Sci & Technol, Trivandrum 695019, Kerala, India

[2] N Maharashtra Univ, Sch Life Sci, Jalgaon 425001, India

来源：

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY | 2010年 / 162卷 / 01期

关键词：

Probiotics; Bile acids; Bile salt hydrolase; Cholesterol; BACTERIAL CHOLYLTAURINE HYDROLASE; LACTOBACILLUS-PLANTARUM; IN-VITRO; BIFIDOBACTERIUM-LONGUM; FUNCTIONAL-ANALYSIS; GENETIC-ANALYSIS; ATOPIC DISEASE; STRAINS; PURIFICATION; CLONING;

D O I：

10.1007/s12010-009-8738-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Probiotic has modernized the current dietetic sense with novel therapeutic and nutritional benefits to the consumers. The presence of bile salt hydrolase (BSH) in probiotics renders them more tolerant to bile salts, which also helps to reduce the blood cholesterol level of the host. This review focuses on the occurrence of bile salt hydrolase among probiotics and its characterization, importance, applications, and genetics involved with recent updates. Research on bile salt hydrolase is still in its infancy. The current perspective reveals a huge market potential of probiotics with bile salt hydrolase. Intensive research in this field is desired to resolve some of the lacunae.

引用

页码：166 / 180

页数：15

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