Preparation and characterization of aliphatic/aromatic copolyesters based on bisphenol-A terephthalate, hexylene terephthalate and lactide mioties

被引:20
作者
Chen, Yiwang
Yang, Yan
Su, Jiying
Tan, Licheng
Wang, Yan
机构
[1] Nanchang Univ, Sch Mat Sci & Engn, Nanchang 330031, Peoples R China
[2] Nanchang Univ, Dept Chem, Nanchang 330031, Peoples R China
[3] Nanchang Univ, Affiliated Hosp 1, Nanchang 330006, Peoples R China
关键词
copolyesters; biodegradation; lactide; aromatic; aliphatic;
D O I
10.1016/j.reactfunctpolym.2007.02.011
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
To obtain higher molecular weight processable polyesters which are of potential interest for tissue engineering, a series of biodegradable aliphatic/aromatic copolyesters, poly(4,4'-isopropylidenediphenyl terephthalate)-co-poly(hexylene terephthalate)-co-polylactide (PBHTL), were synthesized via direct polycondensation from terephthaloyl dichloride, bisphenol-A, 1,6-hexanediol, and oligolactide. The resulting copolyesters, PBHTL, were characterized by proton nuclear magnetic resonance (H-1 NMR), gel permeation chromatography (GPC), differential scanning calorimetry (DSC), thermogravimetry (TG) and wide-angle X-ray scattering (WAXS), and their glass transition temperature (T-g), and thermal decomposition temperature (T-d) were obtained. The PBHTL shows two-step thermal decomposition, which is corresponding to segment of 4,4'-isopropylidenedil)henyl terephthalate (BAT) and segments of hexylene tereplithalate (HT) and lactide (LA), respectively. Due to the incorporation of flexible aliphatic unit into the main chains of copolyesters, PBHTL has lower T-g, and shows enhanced hydrolytic degradability under a physiological conditions with increasing lactide and hexylene moieties. Initial experiments indicated excellent biocompatibility based on cell seeding experiments and microscopic evidence. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:396 / 407
页数:12
相关论文
共 67 条
[1]   Modification of waste poly( ethylene terephthalate) (PET) by using poly(L-lactic acid) (PLA) and hydrolytic stability [J].
Acar, I ;
Kasgöz, A ;
Özgümüs, S ;
Orbay, M .
POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING, 2006, 45 (03) :351-359
[2]  
ASANO M, 1985, MAKROMOL CHEM-RAPID, V6, P509
[3]   Syntheses, characterizations, and structures of a new series of aliphatic-aromatic polyesters. 1. The poly(tetramethylene terephthalate dicarboxylates) [J].
Atfani, M ;
Brisse, F .
MACROMOLECULES, 1999, 32 (23) :7741-7752
[4]   Perfectly alternating copolymer of lactic acid and ethylene oxide as a plasticizing agent for polylactide [J].
Bechtold, K ;
Hillmyer, MA ;
Tolman, WB .
MACROMOLECULES, 2001, 34 (25) :8641-8648
[5]   Design, synthesis, and properties of new biodegradable aromatic/aliphatic liquid crystalline copolyesters [J].
Chen, YW ;
Wombacher, R ;
Wendorff, JH ;
Visjager, J ;
Smith, P ;
Greiner, A .
BIOMACROMOLECULES, 2003, 4 (04) :974-980
[6]   Thermotropic aromatic/lactide copolyesters with solubilizing side chains on aromatic rings [J].
Chen, YW ;
Wombacher, R ;
Wendorff, JH ;
Greiner, A .
POLYMER, 2003, 44 (19) :5513-5520
[7]   Thermotropic aromatic/lactide copolyesters with lateral methoxyethyleneoxy substituents [J].
Chen, YW ;
Wombacher, R ;
Wendorff, JH ;
Greiner, A .
CHEMISTRY OF MATERIALS, 2003, 15 (03) :694-698
[8]   Evaluation of biodegradability of poly(epsilon-caprolactone)/poly(ethylene terephthalate) blends [J].
Chiellini, E ;
Corti, A ;
Giovannini, A ;
Narducci, P ;
Paparella, AM ;
Solaro, R .
JOURNAL OF ENVIRONMENTAL POLYMER DEGRADATION, 1996, 4 (01) :37-50
[9]   A new biodegradable copolyester poly(butylene succinate-co-ethylene succinate-co-ethylene terephthalate) [J].
Deng, LM ;
Wang, YZ ;
Yang, KK ;
Wang, XL ;
Zhou, Q ;
Ding, SD .
ACTA MATERIALIA, 2004, 52 (20) :5871-5878
[10]   Design of segmented poly(ether ester) materials and structures for the tissue engineering of bone [J].
Deschamps, AA ;
Claase, MB ;
Sleijster, WJ ;
de Bruijn, JD ;
Grijpma, DW ;
Feijen, J .
JOURNAL OF CONTROLLED RELEASE, 2002, 78 (1-3) :175-186