A Colorimetric Sensor Array for the Detection of the Date-Rape Drug γ-Hydroxybutyric Acid (GHB): A Supramolecular Approach

被引：60
作者：
Baumes, Laurent A. [1 ]
Sogo, Mireia Buaki [1 ]
Montes-Navajas, Pedro [1 ]
Corma, Avelino [1 ]
Garcia, Hermenegildo [1 ]
机构：
[1] Univ Politecn Valencia, CSIC, Inst Tecnol Quim, Valencia 46022, Spain
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 15期
关键词：
cucurbiturils; drug detection; host-guest systems; sensors; supramolecular chemistry; RATIONAL DESIGN; DYES; IDENTIFICATION; ENCAPSULATION; INTOXICATION; METHODOLOGY; COMPLEXES; ABUSE; COMA; TALE;
D O I：
10.1002/chem.200903127
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
gamma-Hydroxybutyric acid (GHB), a colourless, odourless and tasteless chemical, has become one of the most dangerous illicit drugs of abuse today. At low doses, this drug is a central nervous system depressant that reduces anxiety and produces euphoria and relaxation, sedating the recipient. There is an urgent need for simple, easy-to-use sensors for GHB in solution. Here, we present a colorimetric sensor array based on supramolecular host guest complexes of fluorescent dyes with organic capsules (cucurbiturils) for the detection of GHB.
引用
收藏
页码：4489 / 4495
页数：7
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