A Colorimetric Sensor Array for the Detection of the Date-Rape Drug γ-Hydroxybutyric Acid (GHB): A Supramolecular Approach

被引：60

作者：

Baumes, Laurent A. ^{[1
]}

Sogo, Mireia Buaki ^{[1
]}

Montes-Navajas, Pedro ^{[1
]}

Corma, Avelino ^{[1
]}

Garcia, Hermenegildo ^{[1
]}

机构：

[1] Univ Politecn Valencia, CSIC, Inst Tecnol Quim, Valencia 46022, Spain

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 15期

关键词：

cucurbiturils; drug detection; host-guest systems; sensors; supramolecular chemistry; RATIONAL DESIGN; DYES; IDENTIFICATION; ENCAPSULATION; INTOXICATION; METHODOLOGY; COMPLEXES; ABUSE; COMA; TALE;

D O I：

10.1002/chem.200903127

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

gamma-Hydroxybutyric acid (GHB), a colourless, odourless and tasteless chemical, has become one of the most dangerous illicit drugs of abuse today. At low doses, this drug is a central nervous system depressant that reduces anxiety and produces euphoria and relaxation, sedating the recipient. There is an urgent need for simple, easy-to-use sensors for GHB in solution. Here, we present a colorimetric sensor array based on supramolecular host guest complexes of fluorescent dyes with organic capsules (cucurbiturils) for the detection of GHB.

引用

页码：4489 / 4495

页数：7

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