Case Report: Orbital Tumor Revealing Adult T-Cell Leukemia/Lymphoma Associated with Human T-Cell Lymphotropic Virus Type-1

被引：6

作者：

Fares, Selim ^{[1
]}

Hage, Rabih ^{[1
]}

Pegliasco, Jean ^{[2
]}

Chraibi, Samy ^{[2
]}

Merle, Harold ^{[1
]}

机构：

[1] Martinique Univ Hosp, Dept Ophthalmol, Fort De France, Martinique, France

[2] Martinique Univ Hosp, Dept Hematol, Fort De France, Martinique, France

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2018年 / 99卷 / 02期

关键词：

OCULAR MANIFESTATIONS; LEUKEMIA-LYMPHOMA; INFECTION; SURVIVAL; UVEITIS;

D O I：

10.4269/ajtmh.17-0137

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Adult T-cell Leukemia/Lymphoma (ATLL) is a sight-and life-threatening complication of human T-cell lymphotropic virus type 1 (HTLV-1) infection. Ophthalmic manifestations include uveitis, optic nerve oedema, retinal vasculitis, and lymphomatous infiltration. Orbital lesions are rare. We report the case of an orbital tumor revealing systemic ATLL in a 45-year-old Dominican patient who died despite treatment. Apart from late-grade cutaneous T-cell lymphoma, ATLL is the only T-lymphoma to develop in the orbit. Diagnosis is based on serologic evidence of HTLV-1 infection, cytology, and blood sample analysis. Biopsy is deemed necessary. Given the poor prognosis of ATLL and the worldwide presentation of HTLV-1, physicians should consider ATLL in the differential diagnosis of orbital malignant tumor and look for HTLV-1 infection in populations at risk.

引用

页码：435 / 438

页数：4

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