FUROSTANE-TYPE STEROIDAL SAPONIN FROM Digitalis ciliata

被引：6

作者：

Gvazava, L. N. ^{[1
]}

Kikoladze, V. S. ^{[2
]}

机构：

[1] IG Kutateladze Pharmaceut Chem Inst, GE-0159 Tbilisi, Georgia

[2] PG Melikishvili Phys & Organ Chem Inst, GE-0186 Tbilisi, Georgia

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2010年 / 46卷 / 02期

关键词：

Digitalis ciliata; Scrophulariaceae; steroidal glycoside; furostane; tigogenin; SPECTROSCOPY;

D O I：

10.1007/s10600-010-9579-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new furostane-type steroidal glycoside and derivative of tigogenin (1) was isolated from aqueous wastes from production of the cardiac drug acetyldigitoxin from leaves of Digitalis ciliata Trautv. (Scrophulariaceae) and characterized. The structure of the glycoside was established using physical constants, chemical transformations, and spectral data as 3-O-beta-D-glucopyranosyl-(1 -> 3) [beta-D-fucopyranosyl-(1 -> 2)-beta-D-glucopyranosyl-(1 -> 4)-beta-D-galactopyranosyl-(25R)-5 alpha-furostan-3 beta,22 alpha,26-triol-26-O-beta-D-glucopyranoside.

引用

页码：246 / 249

页数：4

共 13 条

[1] C-13 NMR SPECTRAL INVESTIGATIONS .10. C-13 NMR-SPECTROSCOPY OF STEROIDAL SAPOGENINS AND STEROIDAL SAPONINS [J].

AGRAWAL, PK ;

JAIN, DC ;

GUPTA, RK ;

THAKUR, RS .

PHYTOCHEMISTRY, 1985, 24 (11) :2479-2496

[2]

ALTONA C, 1973, ORG MAGN RESONANCE, V13, P1037

[3]

BOCK K, 1973, TETRAHEDRON LETT, P1037

[4] CATALOG OF INFRARED ABSORPTION SPECTRA OF STEROIDAL SAPOGENIN ACETATES [J].

EDDY, CR ;

WALL, ME ;

SCOTT, MK .

ANALYTICAL CHEMISTRY, 1953, 25 (02) :266-271

[5]

GVAZAVA LN, 2006, KHIM PRIR SOEDIN, P452

[6]

GVAZAVA LN, 2007, KHIM PRIR SOEDIN, P135

[7]

HAKOMORI SI, 1964, J BIOCHEM-TOKYO, V55, P205

[8]

KAWASAKI T, 1974, CHEM PHARM BULL, V22, P2164

[9]

KIYOSAWA S, 1968, CHEM PHARM BULL, V16, P1162

[10]

KOCHETKOV NK, 1967, CARBOHYDRATE CHEM, P43

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