Superoxide Dismutase and Catalase Activities in the Retina during Experimental Diabetes and Electric Stimulation of the Paleocerebellar Cortex

被引:10
作者
Kresyun, N. V. [1 ]
Godlevskii, L. S. [1 ]
机构
[1] Odessa Natl Med Univ, Odessa, Ukraine
关键词
streptozotocin; diabetic retinopathy; superoxide dismutase; catalase; electric stimulation of the cerebellum; LEPTIN;
D O I
10.1007/s10517-014-2723-6
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
In 1.5 months after modeling of streptozotocin-induced diabetes mellitus, superoxide dismutase and catalase activities decreased by 40.7 and 32.0%, respectively, in comparison with the corresponding values in Wistar rats without diabetes. Electric stimulations (100 Hz, 0.25 msec, 50-100 mu A, 2.5 sec) of the paleocerebellar cortex (V-VII lobules) were conducted 3 times a day over 1 month. These stimulations prevented the decrease in antioxidant enzyme activity in rats with experimental diabetes.
引用
收藏
页码:206 / 208
页数:3
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