UV photodissociation of trapped ions following ion mobility separation in a Q-ToF mass spectrometer

被引:46
作者
Bellina, Bruno [1 ]
Brown, Jeffery M. [2 ]
Ujma, Jakub [1 ]
Murray, Paul [2 ]
Giles, Kevin [2 ]
Morris, Michael [2 ]
Compagnon, Isabelle [3 ,4 ]
Barran, Perdita E. [1 ]
机构
[1] Univ Manchester, Manchester Inst Biotechnol, Michael Barber Ctr Collaborat Mass Spectrometry, Manchester M13 9PL, Lancs, England
[2] Waters, Wilmslow, Cheshire, England
[3] Univ Lyon 1, F-69622 Villeurbanne, France
[4] Inst Univ France IUF, Univ Lyon CNRS UMR5306 1, Inst Lumiere Mat, F-75005 Paris, France
基金
英国生物技术与生命科学研究理事会;
关键词
ELECTRON-CAPTURE DISSOCIATION; CHARGED PROTEIN CATIONS; PROTEOMICS; PEPTIDE; SPECTROSCOPY; INSTRUMENT;
D O I
10.1039/c4an01656d
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An ion mobility mass spectrometer has been modified to allow optical interrogation of ions with different mass-to-charge (m/z) ratios and/or mobilities (K). An ion gating and trapping procedure has been developed which allows us to store ions for several seconds enabling UV photodissociation (UVPD).
引用
收藏
页码:6348 / 6351
页数:4
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