BK virus: Current understanding of pathogenicity and clinical disease in transplantation

被引：52

作者：

Chong, Stephanie ^{[1
]}

Antoni, Michelle ^{[2
]}

Macdonald, Andrew ^{[2
]}

Reeves, Matthew ^{[3
]}

Harber, Mark ^{[1
]}

Magee, Ciara N. ^{[1
]}

机构：

[1] UCL, Royal Free Hosp, Dept Renal Med, London, England

[2] Univ Leeds, Fac Biol Sci, Sch Mol & Cellular Biol, London, England

[3] UCL, Royal Free Hosp, Inst Immun & Transplantat, London, England

来源：

REVIEWS IN MEDICAL VIROLOGY | 2019年 / 29卷 / 04期

关键词：

BK virus; transplantation; transplant virology; POLYOMAVIRUS-ASSOCIATED NEPHROPATHY; MINOR CAPSID PROTEINS; RISK-FACTORS; RENAL-TRANSPLANT; HEMORRHAGIC CYSTITIS; ALLOGRAFT NEPHROPATHY; URINARY-EXCRETION; HISTOLOGICAL EVOLUTION; INTERSTITIAL NEPHRITIS; KIDNEY-TRANSPLANTATION;

D O I：

10.1002/rmv.2044

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that continues to pose a significant challenge to clinicians due to its frequently unpredictable onset, persistence, and the lack of effective antiviral agents or prevention strategies. This review covers our current understanding of epidemiology, viral transmission and disease progression, and treatment and prevention strategies that have been used to manage this disease.

引用

页数：14

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