Visualizing and comparing circular genomes using the CGView family of tools

被引:183
作者
Stothard, Paul [1 ]
Grant, Jason R. [1 ]
Van Domselaar, Gary [2 ,3 ]
机构
[1] Univ Alberta, Dept Agr Food & Nutr Sci, Edmonton, AB T6G 2P5, Canada
[2] Natl Microbiol Lab, Bioinformat Lab, Winnipeg, MB, Canada
[3] Univ Manitoba, Dept Med Microbiol, Winnipeg, MB, Canada
关键词
genome visualization; genome analysis; bacteria; organelles;
D O I
10.1093/bib/bbx081
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Graphical genome maps are widely used to assess genome features and sequence characteristics. The CGView (Circular Genome Viewer) software family is a popular collection of tools for generating genome maps for bacteria, organelles and viruses. In this review, we describe the capabilities of the original CGView program along with those of subsequent companion applications, including the CGView Server and the CGView Comparison Tool. We also discuss GView, a graphical user interface-enabled rewrite of CGView, and the GView Server, which offers several integrated analyses for identifying shared or unique genome regions relative to a collection of comparison genomes. We conclude with some remarks about our current development efforts related to CGView aimed at adding new functionality while increasing ease of use.
引用
收藏
页码:1576 / 1582
页数:7
相关论文
共 15 条
[1]   BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons [J].
Alikhan, Nabil-Fareed ;
Petty, Nicola K. ;
Ben Zakour, Nouri L. ;
Beatson, Scott A. .
BMC GENOMICS, 2011, 12
[2]   Circleator: flexible circular visualization of genome-associated data with BioPerl and SVG [J].
Crabtree, Jonathan ;
Agrawal, Sonia ;
Mahurkar, Anup ;
Myers, Garry S. ;
Rasko, David A. ;
White, Owen .
BIOINFORMATICS, 2014, 30 (21) :3125-3127
[3]   Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance [J].
Desjardins, Christopher A. ;
Cohen, Keira A. ;
Munsamy, Vanisha ;
Abeel, Thomas ;
Maharaj, Kashmeel ;
Walker, Bruce J. ;
Shea, Terrance P. ;
Almeida, Deepak V. ;
Manson, Abigail L. ;
Salazar, Alex ;
Padayatchi, Nesri ;
O'Donnell, Max R. ;
Mlisana, Koleka P. ;
Wortman, Jennifer ;
Birren, Bruce W. ;
Grosset, Jacques ;
Earl, Ashlee M. ;
Pym, Alexander S. .
NATURE GENETICS, 2016, 48 (05) :544-+
[4]   The CGView Server: a comparative genomics tool for circular genomes [J].
Grant, Jason R. ;
Stothard, Paul .
NUCLEIC ACIDS RESEARCH, 2008, 36 :W181-W184
[5]   Comparing thousands of circular genomes using the CGView Comparison Tool [J].
Grant, Jason R. ;
Arantes, Adriano S. ;
Stothard, Paul .
BMC GENOMICS, 2012, 13
[6]   Ensembl Genomes 2016: more genomes, more complexity [J].
Kersey, Paul Julian ;
Allen, James E. ;
Armean, Irina ;
Boddu, Sanjay ;
Bolt, Bruce J. ;
Carvalho-Silva, Denise ;
Christensen, Mikkel ;
Davis, Paul ;
Falin, Lee J. ;
Grabmueller, Christoph ;
Humphrey, Jay ;
Kerhornou, Arnaud ;
Khobova, Julia ;
Aranganathan, Naveen K. ;
Langridge, Nicholas ;
Lowy, Ernesto ;
McDowall, Mark D. ;
Maheswari, Uma ;
Nuhn, Michael ;
Ong, Chuang Kee ;
Overduin, Bert ;
Paulini, Michael ;
Pedro, Helder ;
Perry, Emily ;
Spudich, Giulietta ;
Tapanari, Electra ;
Walts, Brandon ;
Williams, Gareth ;
Tello-Ruiz, Marcela ;
Stein, Joshua ;
Wei, Sharon ;
Ware, Doreen ;
Bolser, Daniel M. ;
Howe, Kevin L. ;
Kulesha, Eugene ;
Lawson, Daniel ;
Maslen, Gareth ;
Staines, Daniel M. .
NUCLEIC ACIDS RESEARCH, 2016, 44 (D1) :D574-D580
[7]   SynTView - an interactive multi-view genome browser for next-generation comparative microorganism genomics [J].
Lechat, Pierre ;
Souche, Erika ;
Moszer, Ivan .
BMC BIOINFORMATICS, 2013, 14
[8]   Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes [J].
Nash, John H. E. ;
Villegas, Andre ;
Kropinski, Andrew M. ;
Aguilar-Valenzuela, Renan ;
Konczy, Paulina ;
Mascarenhas, Mariola ;
Ziebell, Kim ;
Torres, Alfredo G. ;
Karmali, Mohamed A. ;
Coombes, Brian K. .
BMC GENOMICS, 2010, 11
[9]  
Nielsen CB, 2010, NAT METHODS, V7, pS5, DOI [10.1038/NMETH.1422, 10.1038/nmeth.1422]
[10]   CiVi: circular genome visualization with unique features to analyze sequence elements [J].
Overmars, Lex ;
van Hijum, Sacha A. F. T. ;
Siezen, Roland J. ;
Francke, Christof .
BIOINFORMATICS, 2015, 31 (17) :2867-2869