Translocases: A bacterial tunnel for drugs and proteins

被引：33
作者：
Lewis, K [1 ]
机构：
[1] Tufts Univ, Ctr Biotechnol, Medford, MA 02155 USA
来源：
CURRENT BIOLOGY | 2000年 / 10卷 / 18期
关键词：
D O I：
10.1016/S0960-9822(00)00682-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Unrelated translocases extrude proteins or antimicrobial agents across both membranes of the cell envelope in Gram-negative bacteria. The TolC protein links the translocases to the external environment. The recently determined crystal structure of TolC shows how this universal tunnel operates.
引用
收藏
页码：R678 / R681
页数：4
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