Translocases: A bacterial tunnel for drugs and proteins

被引:33
|
作者
Lewis, K [1 ]
机构
[1] Tufts Univ, Ctr Biotechnol, Medford, MA 02155 USA
关键词
D O I
10.1016/S0960-9822(00)00682-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Unrelated translocases extrude proteins or antimicrobial agents across both membranes of the cell envelope in Gram-negative bacteria. The TolC protein links the translocases to the external environment. The recently determined crystal structure of TolC shows how this universal tunnel operates.
引用
收藏
页码:R678 / R681
页数:4
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