SOLVENT-FREE MICROWAVE ASSISTED SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW 2-{4-[3-(1-PHENYL-3-ARYL-1H-PYRAZOL-4-YL)-ACRYLOYL]-PHENYL}-ISOINDOLE-1,3-DIONES

被引：0

作者：

Ashok, D. ^{[1
]}

Ganesh, Arram ^{[1
]}

Ravi, S. ^{[1
]}

Lakshmi, B. Vijaya ^{[1
]}

机构：

[1] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 24卷 / 01期

关键词：

INHIBITORS; DERIVATIVES; CHALCONES; PYRAZOLE; AGENTS;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of new 2-{4-[3-(1-phenyl-3-aryl-1H-pyrazol-4-yl)-acryloyl]-phenyl}-isoindole-1,3-diones have been synthesized by Claisen-Schmidt condensation of 2-(4-acetylphenyl)-isoindole-1,3-dione with 1-phenyl-3-aryl-1H-pyrazole-4-carbaldehydes in the presence of basic alumina under solvent-free microwave irradiation and conventional heating methods. All the compounds tested for their in vitro antimicrobial activity against bacterial and fungal organisms and they were characterized on the basis of spectral data such as IR, H-1 NMR, C-13 NMR, mass spectral data and elemental analysis.

引用

页码：29 / 34

页数：6

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