Efficacy of a transdiagnostic cognitive-behavioral intervention for eating disorder psychopathology delivered through a smartphone app: a randomized controlled trial
Background Although effective treatments exist for diagnostic and subthreshold-level eating disorders (EDs), a significant proportion of affected individuals do not receive help. Interventions translated for delivery through smartphone apps may be one solution towards reducing this treatment gap. However, evidence for the efficacy of smartphones apps for EDs is lacking. We developed a smartphone app based on the principles and techniques of transdiagnostic cognitive-behavioral therapy for EDs and evaluated it through a pre-registered randomized controlled trial. Methods Symptomatic individuals (those who reported the presence of binge eating) were randomly assigned to the app (n = 197) or waiting list (n = 195). Of the total sample, 42 and 31% exhibited diagnostic-level bulimia nervosa and binge-eating disorder symptoms, respectively. Assessments took place at baseline, 4 weeks, and 8 weeks post-randomization. Analyses were intention-to-treat. The primary outcome was global levels of ED psychopathology. Secondary outcomes were other ED symptoms, impairment, and distress. Results Intervention participants reported greater reductions in global ED psychopathology than the control group at post-test (d = -0.80). Significant effects were also observed for secondary outcomes (d's = -0.30 to -0.74), except compensatory behavior frequency. Symptom levels remained stable at follow-up. Participants were largely satisfied with the app, although the overall post-test attrition rate was 35%. Conclusion Findings highlight the potential for this app to serve as a cost-effective and easily accessible intervention for those who cannot receive standard treatment. The capacity for apps to be flexibly integrated within current models of mental health care delivery may prove vital for addressing the unmet needs of people with EDs.
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UCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
Khadjesari, Zarnie
;
Murray, Elizabeth
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UCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
Murray, Elizabeth
;
Kalaitzaki, Eleftheria
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MRC Gen Practice Res Framework, London, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
Kalaitzaki, Eleftheria
;
White, Ian R.
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Inst Publ Hlth, MRC Biostat Unit, Cambridge, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
White, Ian R.
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McCambridge, Jim
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London Sch Hyg & Trop Med, Ctr Res Drugs & Hlth Behav, London WC1, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
McCambridge, Jim
;
Thompson, Simon G.
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Inst Publ Hlth, MRC Biostat Unit, Cambridge, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
Thompson, Simon G.
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Wallace, Paul
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UCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
机构:
Michigan State Univ, Dept Psychol, E Lansing, MI 48824 USAMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
Klump, Kelly L.
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Bulik, Cynthia M.
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Univ N Carolina, Sch Med, Dept Psychiat, Chapel Hill, NC USA
Univ N Carolina, Sch Med, Dept Nutr, Chapel Hill, NC USAMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
Bulik, Cynthia M.
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Kaye, Walter H.
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Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USAMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
Kaye, Walter H.
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Treasure, Janet
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机构:
Guys Kings & St Thomas Med Sch, S London & Maudsley NHS Trust, Dept Psychiat, London, EnglandMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
Treasure, Janet
;
Tyson, Edward
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Univ Texas Austin, Dept Kinesiol & Hlth Educ, Austin, TX 78712 USAMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
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Univ Manchester, Div Psychol & Mental Hlth, Fac Biol Med & Hlth, Manchester, Lancs, England
Western Sydney Univ, NICM Hlth Res Inst, Penrith, NSW, AustraliaDeakin Univ, Sch Psychol, 221 Burwood Highway, Burwood, Vic 3125, Australia
Firth, Joseph
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Fuller-Tyszkiewicz, Matthew
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Deakin Univ, Sch Psychol, 221 Burwood Highway, Burwood, Vic 3125, Australia
Deakin Univ, Ctr Social & Early Emot Dev, Burwood, Vic, AustraliaDeakin Univ, Sch Psychol, 221 Burwood Highway, Burwood, Vic 3125, Australia
机构:
UCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
Khadjesari, Zarnie
;
Murray, Elizabeth
论文数: 0引用数: 0
h-index: 0
机构:
UCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
Murray, Elizabeth
;
Kalaitzaki, Eleftheria
论文数: 0引用数: 0
h-index: 0
机构:
MRC Gen Practice Res Framework, London, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
Kalaitzaki, Eleftheria
;
White, Ian R.
论文数: 0引用数: 0
h-index: 0
机构:
Inst Publ Hlth, MRC Biostat Unit, Cambridge, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
White, Ian R.
;
McCambridge, Jim
论文数: 0引用数: 0
h-index: 0
机构:
London Sch Hyg & Trop Med, Ctr Res Drugs & Hlth Behav, London WC1, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
McCambridge, Jim
;
Thompson, Simon G.
论文数: 0引用数: 0
h-index: 0
机构:
Inst Publ Hlth, MRC Biostat Unit, Cambridge, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
Thompson, Simon G.
;
Wallace, Paul
论文数: 0引用数: 0
h-index: 0
机构:
UCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, EnglandUCL, Res Dept Primary Care & Populat Hlth, E Hlth Unit, London NW3 2PF, England
机构:
Michigan State Univ, Dept Psychol, E Lansing, MI 48824 USAMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
Klump, Kelly L.
;
Bulik, Cynthia M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ N Carolina, Sch Med, Dept Psychiat, Chapel Hill, NC USA
Univ N Carolina, Sch Med, Dept Nutr, Chapel Hill, NC USAMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
Bulik, Cynthia M.
;
Kaye, Walter H.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USAMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
Kaye, Walter H.
;
Treasure, Janet
论文数: 0引用数: 0
h-index: 0
机构:
Guys Kings & St Thomas Med Sch, S London & Maudsley NHS Trust, Dept Psychiat, London, EnglandMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
Treasure, Janet
;
Tyson, Edward
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Austin, Dept Kinesiol & Hlth Educ, Austin, TX 78712 USAMichigan State Univ, Dept Psychol, E Lansing, MI 48824 USA
机构:
Univ Manchester, Div Psychol & Mental Hlth, Fac Biol Med & Hlth, Manchester, Lancs, England
Western Sydney Univ, NICM Hlth Res Inst, Penrith, NSW, AustraliaDeakin Univ, Sch Psychol, 221 Burwood Highway, Burwood, Vic 3125, Australia
Firth, Joseph
;
Fuller-Tyszkiewicz, Matthew
论文数: 0引用数: 0
h-index: 0
机构:
Deakin Univ, Sch Psychol, 221 Burwood Highway, Burwood, Vic 3125, Australia
Deakin Univ, Ctr Social & Early Emot Dev, Burwood, Vic, AustraliaDeakin Univ, Sch Psychol, 221 Burwood Highway, Burwood, Vic 3125, Australia