The synthesis of azabicyclic heterocycles

被引：5
|
作者：
Darout, Etzer [1 ]
Basak, Arindrajit [1 ]
机构：
[1] Groton Labs, Pfizer Global Res & Dev, Groton, CT 06340 USA
来源：
TETRAHEDRON LETTERS | 2010年 / 51卷 / 22期
关键词：
KETONES;
D O I：
10.1016/j.tetlet.2010.03.123
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient approach to a oxa-azabicyclo[3.2.1] derivatives has been achieved via a double-Mannich reaction of N,N-bis(methoxymethyl)-1-phenylethanamine with symmetrical and unsymmetrical ketones. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2998 / 3001
页数：4
相关论文
共 50 条
  • [11] I2-mediated and direct synthesis of 3-phenoxy imidazo heterocycles
    Guo, Yanchun
    Wang, Yuexiu
    Xue, Han
    Cao, Shuxia
    Zhao, Yufen
    TETRAHEDRON, 2019, 75 (11) : 1481 - 1491
  • [12] Methods for the synthesis of chiral sulfur heterocycles and their application in the asymmetric Baylis-Hillman reactions
    Periasamy, Mariappan
    Gurubrahamam, Ramani
    Muthukumaragopal, Gopal P.
    TETRAHEDRON-ASYMMETRY, 2013, 24 (9-10) : 568 - 574
  • [13] Facile synthesis of carbo- and heterocycles via Fe(III)-catalyzed alkene hydrofunctionalization
    Qi, Jifeng
    Zheng, Jing
    Cui, Sunliang
    ORGANIC CHEMISTRY FRONTIERS, 2018, 5 (02): : 222 - 225
  • [14] Continuous Flow Synthesis of Five-Membered N-Heterocycles by Ynone System
    Duraisamy, Tamilselvan
    Seenivasan, Vijay Thavasianandam
    Wang, Li-Yu
    Govindan, Karthick
    Ganesan, Balaji
    Kandasamy, Mohanraj
    Chiou, Yu-Ting
    Lin, Wei-Yu
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2025, 14 (01)
  • [15] Synthetic Approach to Alkoxy-β-(trifluoromethyl)styrenes and Their Application in the Synthesis of New Trifluoromethylated Heterocycles
    Muzalevskiy, Vasiliy M.
    Nenajdenko, Valentine G.
    Shastin, Aleksey V.
    Balenkova, Elizabeth S.
    Haufe, Guenter
    SYNTHESIS-STUTTGART, 2009, (13): : 2249 - 2259
  • [16] Synthesis and characterization of new heterocycles containing the 1,2,3-triazole ring system
    Abdel-Wahab, Bakr F.
    Kariuki, Benson M.
    Mohamed, Hanan A.
    El-Hiti, Gamal A.
    JOURNAL OF MOLECULAR STRUCTURE, 2024, 1311
  • [17] Nickel-catalyzed sustainable synthesis of N-heterocycles through dehydrogenative coupling of alcohols
    Bera, Krishanu
    Mukherjee, Arup
    TETRAHEDRON LETTERS, 2021, 81
  • [18] Synthesis of new polyhalogenoalkyl-containing phosphonates with an enaminone core and their use in the preparation of fluorinated heterocycles
    Tarasenko, Karen V.
    Manoylenko, Olga V.
    Kukhar, Valery P.
    Roeschenthaler, Gerd-Volker
    Gerus, Igor I.
    TETRAHEDRON LETTERS, 2010, 51 (35) : 4623 - 4626
  • [19] Carbonylative Acetylation of Heterocycles
    Zhang, Youcan
    Yin, Zhiping
    Wu, Xiao-Feng
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2020, 2020 (02) : 213 - 216
  • [20] Amidoboronates: bringing together the synthesis of BN-heterocycles via a reductive coupling and dynamic covalent chemistry
    McConnell, Anna J.
    DALTON TRANSACTIONS, 2023, 52 (27) : 9189 - 9201
12345