Total synthesis of baicalein

被引:20
作者
Chen, Duo-Zhi [1 ]
Yang, Jian [1 ]
Yang, Bo [1 ]
Wu, Yuan-Shuang [1 ]
Wu, Ting [1 ]
机构
[1] Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kunming 650224, Peoples R China
关键词
baicalein; helilandin B; demethylate; synthesis;
D O I
10.1080/10286020903508416
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
In this paper, a simple and novel synthesis of baicalein is described. This transformation features the novel synthesis of helilandin B and a different way to demethylate. The overall yield of 59% is acceptable. [image omitted].
引用
收藏
页码:124 / 128
页数:5
相关论文
共 6 条
[1]  
AGASIMUNDIN YS, 1973, J CHEM SOC P1, V5, P503
[2]   Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death [J].
Lee, HH ;
Yang, LL ;
Wang, CC ;
Hu, SY ;
Chang, SF ;
Lee, YH .
BRAIN RESEARCH, 2003, 986 (1-2) :103-113
[3]  
RONA L, 2008, AM J HYPERTENS, V21, P219
[4]  
Schultz TW, 2002, ENVIRON TOXICOL, V17, P14, DOI 10.1002/tox.10027.abs
[5]  
SHAW JJ, 2004, Patent No. 2004242907
[6]   Nitrogen-containing flavonoid analogues as CDK1/cyclin B inhibitors: Synthesis, SAR analysis, and biological activity [J].
Zhang, Shixuan ;
Ma, Jigang ;
Bao, Yongming ;
Yang, Puwen ;
Zou, Liang ;
Li, Kangjian ;
Sun, Xiaodan .
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (15) :7127-7132