Photoactive molecules for applications in molecular imaging and cell biology

被引：132

作者：

Shao, Qing ^{[1
]}

Xing, Bengang ^{[1
]}

机构：

[1] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore, Singapore

来源：

CHEMICAL SOCIETY REVIEWS | 2010年 / 39卷 / 08期

关键词：

REGULATING GENE-EXPRESSION; UNNATURAL AMINO-ACIDS; PHOTOCHEMICAL PROPERTIES; CATALYTIC SUBUNIT; RNA DIGESTION; PHOTO-CONTROL; LIGHT; PROTEIN; PHOTORELEASE; ADHESION;

D O I：

10.1039/b915574k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Photoactive technology has proven successful for non-invasive regulation of biological activities and processes in living cells. With the light-directed generation of biomaterials or signals, mechanisms in cell biology can be investigated at the molecular level with spatial and temporal resolution. In this tutorial review, we aim to introduce the important applications of photoactive molecules for elucidating cell biology on aspects of protein engineering, fluorescence labelling, gene regulation and cell physiological functions.

引用

页码：2835 / 2846

页数：12

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