Studies on the anti-inflammatory, antipyretic and analgesic properties of the leaves of Aegle marmelos Corr.

被引:95
作者
Arul, V
Miyazaki, S
Dhananjayan, R
机构
[1] Univ Madras, Dept Pharmacol & Environm Toxicol, Dr ALM Post Grad Inst Basic Med Sci, Madras 600113, Tamil Nadu, India
[2] Natl Inst Anim Hlth, Dept Safety Res, Toxicopharmacol Lab, Tsukuba, Ibaraki 3050856, Japan
关键词
Aegle marmelos Corr; anti-inflammatory; analgesic; antipyretic; Antinociceptive; hyperpyroxia; carrageenan; paw oedema; cotton-pellet; granuloma;
D O I
10.1016/j.jep.2004.09.013
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The serial extracts of the leaves of Aegle marmelos Corr. were investigated for anti-inflammatory property. The analgesic and antipyretic properties were also evaluated. The most of the extracts derived from the plant Aegle marmelos caused a significant inhibition of the carrageenan-induced paw oedema and cotton-pellet granuloma in rats. The extracts also produced marked analgesic activity by reduction the early and late phases of paw licking in mice. A significant reduction in hyperpyrexia in rats was also produced by the most of the extracts. This study was established anti-inflammatory, antinociceptive and antipyretic activities of the leaves of Aegle marmelos. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:159 / 163
页数:5
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