Gold nanoparticles functionalized with cresyl violet and porphyrin via hyaluronic acid for targeted cell imaging and phototherapy

被引：31
作者：
Song, Yanchao [1 ,2 ]
Wang, Zhe [1 ]
Li, Lihong [1 ]
Shi, Wen [1 ]
Li, Xiaohua [1 ]
Ma, Huimin [1 ]
机构：
[1] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Analyt Chem Living Biosyst, Beijing 100190, Peoples R China
[2] Chinese Ctr Dis Control & Prevent, Natl Inst Radiol Protect, Key Lab Radiol Protect & Nucl Emergency, Beijing 100088, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 99期
关键词：
IN-VIVO; DRUG-DELIVERY; QUANTUM DOTS; CANCER; NANOPROBE; THERAPY; AGENT; PROBE;
D O I：
10.1039/c4cc07565j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Gold nanoparticles are functionalized as a nanoprobe with cresyl violet and porphyrin via hyaluronic acid. The nanoprobe becomes highly fluorescent in the presence of hyaluronidase or under ultraviolet irradiation, and can be used to target cancer cells via the overexpressed CD44 receptor for fluorescence imaging and phototherapy.
引用
收藏
页码：15696 / 15698
页数：3
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