The use of nanotechnology in cardiovascular disease

被引:67
作者
Chandarana, Meera [1 ]
Curtis, Anthony [1 ]
Hoskins, Clare [1 ]
机构
[1] Keele Univ, Inst Sci & Technol Med, Sch Pharm, Keele ST5 5BG, Staffs, England
关键词
Nanomedicine; Cardiovascular disease; Nanotechnology; Medical therapeutics; DRUG-DELIVERY; IN-VITRO; POLYMERIC NANOPARTICLES; MAGNETIC-RESONANCE; ATHEROSCLEROTIC LESIONS; CARDIAC DYSFUNCTION; MIXED MICELLES; DENDRIMER; LIPOSOMES; VASODILATION;
D O I
10.1007/s13204-018-0856-z
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Cardiovascular diseases claim a number of lives globally; many of which are preventable. With the increase in diets that consist of high saturated fat, salt, and sugar, people often living sedentary lifestyles, and a rise in cases of obesity, the incidence of cardiovascular disease is increasing. These contributing factors, coupled with more advanced methods of diagnosis, have delivered statistics that clearly show that there is a rising trend in the prevalence of cardiovascular disease. Treatment for cardiovascular diseases is limited currently to oral medicines or invasive surgery. There is a huge gap in this area of medicine for novel therapeutics for improved patient outcomes. Nanotechnology may provide a solution to more effective treatment of disease, with better prognoses and a reduced side effect profile. This review will explore for potential solutions to the limited pharmacological therapies currently on the market and the future that lies ahead for the place of nanotechnology within cardiovascular medicine.
引用
收藏
页码:1607 / 1619
页数:13
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