Multidimensional assessment of differences in monoamine metabolism in C57Bl/6 acid BALB/c mice

被引：3
|
作者：
Seredenin, SB [1 ]
Lapitskaya, AS [1 ]
Nadorov, SA [1 ]
Kudrin, VS [1 ]
Badyshtov, BA [1 ]
机构：
[1] Russian Acad Med Sci, Inst Pharmacol, Dept Mol Genet, Moscow 109801, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2000年 / 129卷 / 05期
关键词：
inbred mice; brain; monoamines; stress;
D O I：
10.1007/BF02439811
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Monoamine metabolism in the hypothalamus and striatum of BALB/c and C57B1/6 mice (intact and stressed in the open field test) was studied using single- and multidimensional statistical methods. It is suggested that the revealed difference in neurotransmitter metabolism is associated with genetically controlled behavior of these animals under conditions of emotional stress. The results of discriminant analysis suggest that the regulation of monoamine metabolism during emotional stress is genetically determined.
引用
收藏
页码：487 / 490
页数：4
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