Adolescent Social Functioning Deficits in Association With Adoptive Family Functioning and Genetic Risk for Schizophrenia Spectrum Disorders The Finnish Adoptive Family Study of Schizophrenia

被引：1

作者：

Tikkanen, Ville ^{[1
]}

Siira, Virva ^{[2
]}

Wahlberg, Karl-Erik ^{[1
]}

Hakko, Helina ^{[3
]}

Myllyaho, Toni ^{[1
]}

Laksy, Kristian ^{[4
]}

Roisko, Riikka ^{[3
]}

Niemela, Mika ^{[3
,5
]}

Rasanen, Sami ^{[1
,3
]}

机构：

[1] Univ Oulu, Fac Med, Res Unit Clin Neurosci, Psychiat, POB 5000, Oulu 90014, Finland

[2] Univ Oulu, Fac Educ, Oulu, Finland

[3] Oulu Univ Hosp, Dept Psychiat, Oulu, Finland

[4] Social Secur Inst Finland SST, Helsinki, Finland

[5] Univ Oulu, Ctr Life Course Hlth Res, Fac Med, Oulu, Finland

来源：

JOURNAL OF NERVOUS AND MENTAL DISEASE | 2022年 / 210卷 / 06期

关键词：

Social functioning; adolescence; family functioning; genetic risk; adoption study; GENOTYPE-ENVIRONMENT INTERACTION; COMMUNICATION DEVIANCE; VULNERABILITY; PARENTS; STRESS; MODEL; INDIVIDUALS; ADJUSTMENT; LIABILITY; HEALTH;

D O I：

10.1097/NMD.0000000000001483

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Social functioning deficits (SFDs) during adolescence represent potential vulnerability indicators to schizophrenia spectrum disorders, but little is known about how both family environmental and genetic factors contribute to SFDs. The aim of this study was to examine the association of adoptees' adolescent social functioning with adoptive family functioning and adoptees' high (HR) or low (LR) genetic risk for schizophrenia spectrum disorders. The present subsample from the nationwide Finnish Adoptive Family Study of Schizophrenia included 88 HR and 83 LR adoptees. Adolescent social functioning was assessed using UCLA Social Attainment Survey. Assessment of adoptive family functioning was based on Global Family Ratings. Results indicated that dysfunctional family processes and high genetic risk for schizophrenia spectrum disorders contributed approximately equally to adoptees' adolescent social functioning. Our findings underscore the importance of functional family processes in adolescent social functioning, particularly in individuals at high genetic risk for severe psychiatric disorder.

引用

页码：418 / 425

页数：8

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