Instruments of microbial warfare: bacteriocin synthesis, toxicity and immunity

被引:72
作者
Baba, T [1 ]
Schneewind, O [1 ]
机构
[1] Univ Calif Los Angeles, Sch Med, Dept Microbiol & Immunol, Los Angeles, CA 90095 USA
关键词
D O I
10.1016/S0966-842X(97)01196-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Bacteria have devised ingenious enzymatic machinery to synthesize antibiotic molecules (bacteriocins) for their continuous warfare with other microorganisms. Synthesis and export of these toxic compounds are coordinated to ensure the proper extracellular activation of bacteriocin toxicity. In designing future antibiotics, some of the tricks used by bacteriocins might be exploited for the synthesis of novel compounds.
引用
收藏
页码:66 / 71
页数:6
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