Case of autoimmune hepatitis with overlap systemic lupus erythematosus

被引:1
作者
Goyes, Daniela [1 ]
Malladi, Vijayram R. [2 ]
Ishtiaq, Rizwan [3 ]
Al-Khazraji, Ahmed [4 ]
机构
[1] Beth Israel Deaconess Med Ctr, Gastroenterol & Hepatol, Boston, MA 02215 USA
[2] Univ Kansas, Sch Med, Internal Med, Wichita, KS 67214 USA
[3] Mercy St Vicent Med Ctr, Internal Med, Toledo, OH USA
[4] Icahn Sch Med Mt Sinai Elmhurst Hosp, Gastroenterol & Hepatol, New York, NY USA
关键词
liver disease; rheumatology; DIAGNOSIS; ASSOCIATION;
D O I
10.1136/bcr-2020-237341
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Autoimmune hepatitis (AIH) is an autoimmune liver disease characterised by the presence of autoantibodies including antinuclear antibodies, anti-smooth muscle antibody and hypergammaglobulinaemia. Systemic lupus erythematosus (SLE) is a systemic disease that can affect multiple organs. Coexistence of AIH and SLE as an overlap syndrome occurs in about 1%-2.6% of the AIH cases. Since both conditions share common autoimmune features, their coexistence can pose a diagnostic dilemma which can result in a delay in treatment. We present here a challenging case of a middle-aged woman with AIH in remission who later developed new-onset fatigue, pleural effusion and splenomegaly.
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页数:4
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共 19 条
[1]   International Autoimmune Hepatitis Group Report:: review of criteria for diagnosis of autoimmune hepatitis [J].
Alvarez, E ;
Berg, PA ;
Bianchi, FB ;
Bianchi, L ;
Burroughs, AK ;
Cancado, EL ;
Chapman, RW ;
Cooksley, WGE ;
Czaja, AJ ;
Desmet, VJ ;
Donaldson, RT ;
Eddleston, ALWF ;
Fainboim, L ;
Heathcote, J ;
Homberg, JC ;
Hoofnagle, JH ;
Kakumu, S ;
Krawitt, EL ;
Mackay, IR ;
MacSween, RNM ;
Maddrey, WC ;
Manns, MP ;
McFarlane, IG ;
zum Büschenfelde, KHM ;
Mieli-Vergani, G ;
Nakanuma, Y ;
Nishioka, M ;
Penner, E ;
Porta, G ;
Portmann, BC ;
Reed, WD ;
Rodes, J ;
Schalm, SW ;
Scheuer, PJ ;
Schrumpf, E ;
Seki, T ;
Toda, G ;
Tsuji, T ;
Tygstrup, N ;
Vergani, D ;
Zeniya, M .
JOURNAL OF HEPATOLOGY, 1999, 31 (05) :929-938
[2]  
Aringer M, 2019, ARTHRITIS RHEUMATOL, V71, P1400, DOI [10.1002/art.40930, 10.1136/annrheumdis-2018-214819]
[3]   Association of autoimmune hepatitis and systemic lupus erythematodes: A case series and review of the literature [J].
Beisel, Claudia ;
Weiler-Normann, Christina ;
Teufel, Andreas ;
Lohse, Ansgar W. .
WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (35) :12662-12667
[4]   Challenge of liver disease in systemic lupus erythematosus: Clues for diagnosis and hints for pathogenesis [J].
Bessone, Fernando ;
Poles, Natalia ;
Roma, Marcelo G. .
WORLD JOURNAL OF HEPATOLOGY, 2014, 6 (06) :394-409
[5]   Characteristics of pleural effusions in systemic lupus erythematosus: differential diagnosis of lupus pleuritis [J].
Choi, B. Y. ;
Yoon, M. J. ;
Shin, K. ;
Lee, Y. J. ;
Song, Y. W. .
LUPUS, 2015, 24 (03) :321-326
[6]   Liver abnormalities in connective tissue diseases [J].
De Santis, Maria ;
Crotti, Chiara ;
Selmi, Carlo .
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2013, 27 (04) :543-551
[7]   Systemic lupus erythematosus and autoimmune hepatitis [J].
Efe, Cumali ;
Purnak, Tugrul ;
Ozaslan, Ersan .
RHEUMATOLOGY INTERNATIONAL, 2011, 31 (03) :419-419
[8]  
Gemery John M, 2016, BMC Hematol, V16, P3, DOI 10.1186/s12878-016-0042-z
[9]   Autoimmune hepatitis [J].
Heneghan, Michael A. ;
Yeoman, Andrew D. ;
Verma, Sumita ;
Smith, Alastair D. ;
Longhi, Maria Serena .
LANCET, 2013, 382 (9902) :1433-1444
[10]   Simplified criteria for the diagnosis of autoimmune hepatitis [J].
Hennes, Elke M. ;
Zeniya, Mikio ;
Czaja, Albert. J. ;
Pares, Albert ;
Dalekos, George N. ;
Krawitt, Edward L. ;
Bittencourt, Paulo L. ;
Porta, Gilda ;
Boberg, Kirsten M. ;
Hofer, Harald ;
Bianchi, Francesco B. ;
Shibata, Minoru ;
Schramm, Christoph ;
de Torres, Barbara Eisenmann ;
Galle, Peter R. ;
McFarlane, Ian ;
Dienes, Hans-Peter ;
Lohse, Ansgar W. .
HEPATOLOGY, 2008, 48 (01) :169-176