Tumor-selective catalytic nanosystem for activatable theranostics

被引:42
作者
Duan, Lu-Ying [1 ]
Wang, Yu-Jie [1 ]
Liu, Jin-Wen [1 ]
Wang, Yu-Min [1 ]
Li, Na [1 ]
Jiang, Jian-Hui [1 ]
机构
[1] Hunan Univ, Inst Chem Biol & Nanomed, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
基金
中国博士后科学基金; 中国国家自然科学基金;
关键词
HYDROGEN-PEROXIDE; CANCER-THERAPY; NANOPARTICLES; CYTOTOXICITY; HALLMARKS; EFFICIENT;
D O I
10.1039/c8cc03922d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel tumor-selective catalytic nanosystem that enables efficient chemodynamic therapy (CDT) and activatable fluorescence imaging in H2O2-rich tumor microenvironments has been developed.
引用
收藏
页码:8214 / 8217
页数:4
相关论文
共 25 条
[1]   Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells [J].
AshaRani, P. V. ;
Mun, Grace Low Kah ;
Hande, Manoor Prakash ;
Valiyaveettil, Suresh .
ACS NANO, 2009, 3 (02) :279-290
[2]   An Activatable Theranostic for Targeted Cancer Therapy and Imaging** [J].
Bhuniya, Sankarprasad ;
Maiti, Sukhendu ;
Kim, Eun-Joong ;
Lee, Hyunseung ;
Sessler, Jonathan L. ;
Hong, Kwan Soo ;
Kim, Jong Seung .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (17) :4469-4474
[3]   Rethinking cancer nanotheranostics [J].
Chen, Hongmin ;
Zhang, Weizhong ;
Zhu, Guizhi ;
Xie, Jin ;
Chen, Xiaoyuan .
NATURE REVIEWS MATERIALS, 2017, 2 (07)
[4]   An H2O2-responsive nanocarrier for dual-release of platinum anticancer drugs and O2: controlled release and enhanced cytotoxicity against cisplatin resistant cancer cells [J].
Chen, Huachao ;
He, Weijiang ;
Guo, Zijian .
CHEMICAL COMMUNICATIONS, 2014, 50 (68) :9714-9717
[5]   Hydrogen peroxide in the human body [J].
Halliwell, B ;
Clement, MV ;
Long, LH .
FEBS LETTERS, 2000, 486 (01) :10-13
[6]   The hallmarks of cancer [J].
Hanahan, D ;
Weinberg, RA .
CELL, 2000, 100 (01) :57-70
[7]   Tumor-selective catalytic nanomedicine by nanocatalyst delivery [J].
Huo, Minfeng ;
Wang, Liying ;
Chen, Yu ;
Shi, Jianlin .
NATURE COMMUNICATIONS, 2017, 8
[8]   ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis [J].
Ishikawa, Kaori ;
Takenaga, Keizo ;
Akimoto, Miho ;
Koshikawa, Nobuko ;
Yamaguchi, Aya ;
Imanishi, Hirotake ;
Nakada, Kazuto ;
Honma, Yoshio ;
Hayashi, Jun-Ichi .
SCIENCE, 2008, 320 (5876) :661-664
[9]   Continuous O2-Evolving MnFe2O4 Nanoparticle-Anchored Mesoporous Silica Nanoparticles for Efficient Photodynamic Therapy in Hypoxic Cancer [J].
Kim, Jonghoon ;
Cho, Hye Rim ;
Jeon, Hyejin ;
Kim, Dokyoon ;
Song, Changyeong ;
Lee, Nohyun ;
Choi, Seung Hong ;
Hyeon, Taeghwan .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (32) :10992-10995
[10]   Nanoparticles based on quantum dots and a luminol derivative: implications for in vivo imaging of hydrogen peroxide by chemiluminescence resonance energy transfer [J].
Lee, Eun Sook ;
Deepagan, V. G. ;
You, Dong Gil ;
Jeon, Jueun ;
Yi, Gi-Ra ;
Lee, Jung Young ;
Lee, Doo Sung ;
Suh, Yung Doug ;
Park, Jae Hyung .
CHEMICAL COMMUNICATIONS, 2016, 52 (22) :4132-4135