Inhaled corticosteroid nonadherence and immediate avoidable medical events in older adults with chronic pulmonary ailments

被引:16
作者
Balkrishnan, R
Christensen, DB
机构
[1] Wake Forest Univ, Bowman Gray Sch Med, Dept Publ Hlth Sci, Sect Social Sci & Hlth Policy, Winston Salem, NC 27157 USA
[2] Wake Forest Univ, Bowman Gray Sch Med, Asthma Ctr, Sect Pulm & Crit Care Med, Winston Salem, NC 27157 USA
[3] Univ N Carolina, Sch Pharm, Div Pharmaceut Policy & Evaluat Sci, Chapel Hill, NC USA
关键词
asthma; COPD; case-control study; case-crossover study; medication adherence; inhaled corticosteroids; older adults; adverse medical outcomes;
D O I
10.3109/02770900009055478
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
This study examined the association between nonadherence to inhaled corticosteroids and risk of an immediate avoidable medical event (emergency department visit and hospitalization) in elderly patients with chronic pulmonary ailments. The study comprised a cross-sectional analysis comparing patients with and without avoidable medical event occurrence in each year for adherence preceding the event, and a case-crossover analysis examining the same patient's adherence in years with and without events. The cross-sectional study showed risk odds reductions of nearly 20% in the partially adherent patient, and 40% in the adherent patient compared to the nonadherent patient, after controlling for potential group differences.
引用
收藏
页码:511 / 517
页数:7
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