Challenges and advances in optical 3D mesoscale imaging

被引:10
|
作者
Munck, Sebastian [1 ,2 ,3 ]
Cawthorne, Christopher [4 ]
Escamilla-Ayala, Abril [1 ,2 ,3 ]
Kerstens, Axelle [1 ,2 ,3 ]
Gabarre, Sergio [1 ,2 ,3 ]
Wesencraft, Katrina [5 ]
Battistella, Eliana [5 ]
Craig, Rebecca [5 ]
Reynaud, Emmanuel G. [6 ]
Swoger, Jim [7 ]
McConnell, Gail [5 ]
机构
[1] VIB KU Leuven Ctr Brain & Dis Res, Light Microscopy Expertise Unit, O&N5 Herestr 49,Box 602, B-3000 Leuven, Belgium
[2] VIB BioImaging Core, O&N5 Herestr 49,Box 602, B-3000 Leuven, Belgium
[3] Leuven Brain Inst, KU Leuven Dept Neurosci, Leuven, Belgium
[4] Katholieke Univ Leuven, MoSAIC Mol Small Anim Imaging Ctr, Leuven, Belgium
[5] Univ Strathclyde, Dept Phys, SUPA, Glasgow, Lanark, Scotland
[6] Univ Coll Dublin, Sch Biomol & Biomed Sci, Dublin, Bel Field, Ireland
[7] European Mol Biol Lab EMBL Barcelona, Barcelona, Spain
基金
英国医学研究理事会; 英国生物技术与生命科学研究理事会; 英国工程与自然科学研究理事会;
关键词
3D imaging; absorption; clearing; light sheet microscopy; Mesolens; mesoscale; optical projection tomography; scattering; PROJECTION TOMOGRAPHY; ARTIFICIAL-INTELLIGENCE; HIGH-SPEED; IN-VIVO; BIOLOGICAL TISSUES; WHOLE-BRAIN; MICROSCOPY; DEEP; RECONSTRUCTION; RESOLUTION;
D O I
10.1111/jmi.13109
中图分类号
TH742 [显微镜];
学科分类号
摘要
Optical mesoscale imaging is a rapidly developing field that allows the visualisation of larger samples than is possible with standard light microscopy, and fills a gap between cell and organism resolution. It spans from advanced fluorescence imaging of micrometric cell clusters to centimetre-size complete organisms. However, with larger volume specimens, new problems arise. Imaging deeper into tissues at high resolution poses challenges ranging from optical distortions to shadowing from opaque structures. This manuscript discusses the latest developments in mesoscale imaging and highlights limitations, namely labelling, clearing, absorption, scattering, and also sample handling. We then focus on approaches that seek to turn mesoscale imaging into a more quantitative technique, analogous to quantitative tomography in medical imaging, highlighting a future role for digital and physical phantoms as well as artificial intelligence.
引用
收藏
页码:201 / 219
页数:19
相关论文
共 50 条
  • [41] Printing, Characterizing, and Assessing Transparent 3D Printed Lenses for Optical Imaging
    Rooney, Liam M.
    Christopher, Jay
    Watson, Ben
    Kumar, Yash Susir
    Copeland, Laura
    Walker, Lewis D.
    Foylan, Shannan
    Amos, William B.
    Bauer, Ralf
    McConnell, Gail
    ADVANCED MATERIALS TECHNOLOGIES, 2024, 9 (15)
  • [42] Methodology for Optical Imaging of NAPL 3D Distribution in Transparent Porous Media
    Kashuk, Sina
    Mercurio, Sophia R.
    Iskander, Magued
    GEOTECHNICAL TESTING JOURNAL, 2015, 38 (05): : 603 - 619
  • [43] 3D optical microscopy method based on synthetic aperture integral imaging
    Lee, Joon-Jae
    Shin, Donghak
    Lee, Byung-Gook
    Yoo, Hoon
    3D RESEARCH, 2012, 3 (04) : 1 - 6
  • [44] Considerations for using optical clearing techniques for 3D imaging of nanoparticle biodistribution
    Arms, Lauren
    Robson, Annie-Louise
    Woldu, Ameha
    Martin, Antony
    Palmer, William
    Flynn, Jamie
    Hua, Susan
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 588
  • [45] High-Throughput 3D Imaging Flow Cytometry of Suspended Adherent 3D Cell Cultures
    Yamashita, Minato
    Tamamitsu, Miu
    Kirisako, Hiromi
    Goda, Yuki
    Chen, Xiaoyao
    Hattori, Kazuki
    Ota, Sadao
    SMALL METHODS, 2024, 8 (08)
  • [46] 3D optical microscopy using digital holography
    Stern, A.
    Javidi, Bahram
    SPECIAL SESSIONS ON FOOD SAFETY, VISUAL ANALYTICS, RESOURCE RESTRICTED EMBEDDED AND SENSOR NETWORKS, AND 3D IMAGING AND DISPLAY, 2008, 6983
  • [47] Advances and challenges in precision imaging
    Hricak, Hedvig
    Mayerhoefer, Marius E.
    Herrmann, Ken
    Lewis, Jason S.
    Pomper, Martin G.
    Hess, Christopher P.
    Riklund, Katrine
    Scott, Andrew M.
    Weissleder, Ralph
    LANCET ONCOLOGY, 2025, 26 (01) : e34 - e45
  • [48] 3D object tracking using integral imaging with mutual information and Bayesian optimization
    Wani, Pranav
    Usmani, Kashif
    Krishnan, Gokul
    Javidi, Bahram
    OPTICS EXPRESS, 2024, 32 (05) : 7495 - 7512
  • [49] Scanning all-fiber-optic endomicroscopy system for 3D nonlinear optical imaging of biological tissues
    Wu, Yicong
    Leng, Yuxin
    Xi, Jiefeng
    Li, Xingde
    OPTICS EXPRESS, 2009, 17 (10): : 7907 - 7915
  • [50] Smaller, Faster, Brighter: Advances in Optical Imaging of Living Plant Cells
    Shaw, Sidney L.
    Ehrhardt, David W.
    ANNUAL REVIEW OF PLANT BIOLOGY, VOL 64, 2013, 64 : 351 - 375