STATISTICAL ANALYSIS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATIONS IN CLINICAL STUDIES: EXPECTATIONS AND LIMITATIONS

被引：0

作者：

Gillissen, A. ^{[1
]}

Glaab, T. ^{[2
]}

Lewis, M. ^{[3
]}

Buhl, R. ^{[2
]}

Worth, H.

机构：

[1] Robert Koch Hosp, St George Med Ctr, Leipzig, Germany

[2] Univ Hosp, Dept Pulm, Mainz, Germany

[3] FISPE Epidemiol GmbH, Berlin, Germany

来源：

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 2009年 / 60卷

关键词：

chronic obstructive pulmonary disease; exacerbation; statistics; INHALED CORTICOSTEROIDS; LUNG-FUNCTION; FLUTICASONE PROPIONATE; COPD EXACERBATIONS; BETA-AGONISTS; MORTALITY; TIOTROPIUM; OUTCOMES; METAANALYSIS; SALMETEROL;

D O I：

暂无

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Acute exacerbations of chronic obstructive pulmonary disease (COPD) occur more frequently with increasing COPD severity and are associated with increased morbidity, reduced quality of life, and increased risk of mortality. The prevention and assessment of exacerbations, as a clinically and therapeutically relevant parameter, is a central aspect of clinical COPD studies. The aim of this review is to identify pittfalls in the analysis of the parameter of exacerbation and to describe the criteria that need to be considered in the statistical analysis of exacerbation studies.

引用

页码：7 / 11

页数：5

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