Novel synthesis of barbiturates

被引：25

作者：

Ashnagar, Alamdar ^{[1
]}

Gharib Naseri, Nahid

Sheeri, Behrang

机构：

[1] Ahwaz Jundi Shapour Univ Med Sci, Sch Pharm, Ahvaz 6173944871, Iran

[2] Petr Univ Technol, Ahwaz Fac Petr Engn, Ahvaz 6173944871, Iran

来源：

CHINESE JOURNAL OF CHEMISTRY | 2007年 / 25卷 / 03期

关键词：

barbiturate; barbituric acid; Knovenagel reaction; 5-(indol-3-ylmethylidene)barbituric acid; 5-(thien-2-ylmethylidee)barbituric acid;

D O I：

10.1002/cjoc.200790073

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Knovenagel reaction of barbituric acid with different aldehydes were used to synthesize new barbiturates. This is a novel method which can be used to synthsis various types of new generation of barbiturates which are different from the previously reported.

引用

页码：382 / 384

页数：3

共 11 条

[1]

Bogue J. Y., 1953, BRIT J PHARMACOL, P230

[2]

DASS IND, 1938, P INDIAN ACAD SCI A, V8, P145

[3] ANTICONVULSANT ACTIVITY AND SUCCINATE-DEHYDROGENASE INHIBITORY PROPERTY OF NEW SUBSTITUTED THIOBARBITURATES [J].

DHASMANA, A ;

BARTHWAL, JP ;

PANDEY, BR ;

ALI, B ;

BHARGAVA, KP ;

PARMAR, SS .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1981, 18 (03) :635-637

[4]

Doran W. J., 1959, BARBITURIC ACID HYPN, V4, P5

[5]

Foye W.O., 1974, PRINCIPLES MED CHEM, P165

[6]

GOODMAN LS, 1970, PHARMACOL BASIS, pCH9

[7] BAEYER,ADOLF,VON AND THE NAMING OF BARBITURIC-ACID [J].

KAUFFMAN, GB .

JOURNAL OF CHEMICAL EDUCATION, 1980, 57 (03) :222-223

[8]

RAY OS, 1972, DRUGS SOC HUMAN BEHA, pCH11

[9]

SINGH S, 1980, INDIAN J CHEM B, V19, P625

[10]

VASEY CH, 1955, Patent No. 741097

← 1 2 →