Metal-Free 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-Mediated Cross-Dehydrogenative-Coupling (CDC) of Benzylic C(sp3)-H Bonds and Vinylic C(sp2)-H Bonds: Efficient One-Pot Synthesis of 1H-Indenes

被引：41

作者：

Wang, He ^{[1
]}

Zhao, Yu-Long ^{[1
]}

Li, Lei ^{[1
]}

Li, Sha-Sha ^{[1
]}

Liu, Qun ^{[1
]}

机构：

[1] NE Normal Univ, Dept Chem, Changchun 130024, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 14-15期

关键词：

alkenes; benzylic compounds; C-C coupling; 2,3-dichloro-5,6-dicyanoquinone (DDQ); indenes; C-H ACTIVATION; DERIVATIVES; STRATEGY; MILD; FUNCTIONALIZATION; REARRANGEMENT; CONSTRUCTION; CYCLIZATION; COMPLEXES; ETHYLENE;

D O I：

10.1002/adsc.201400357

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A novel 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-promoted intermolecular crossdehydrogenative coupling reaction of alkyl C(sp(3))-H bonds not adjacent to heteroatoms with vinylic C(sp(2))-H bonds has been developed. This new strategy provides a new, environmentally friendly, and efficient protocol for the synthesis of polysubstituted 1H-indenes in a single step via a radical-initiated two C(sp(2))-C(sp(2)) and C(sp(2))-C(sp(3)) bond formation process.

引用

页码：3157 / 3163

页数：7

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