Circular dichroism and the anomeric configuration of C-glycofuranosyl-2-phenyl-2H-1,2,3-triazoles

被引：6

作者：

Sallam, MAE ^{[1
]}

机构：

[1] Univ Alexandria, Fac Sci, Dept Chem, Alexandria, Egypt

来源：

ENANTIOMER | 2002年 / 7卷 / 06期

关键词：

anomeric configuration; circular dichroism; Cotton effect; C-nucleosides; 1,2,3-triazoles;

D O I：

10.1080/10242430215712

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Circular dichroism spectra of a series of 4-(tetra-hydroxy-tetryl-1-yl)-2-phenyl-2H-1,2,3-triazoles were measured and the sign of their Cotton effects was correlated to the absolute configuration of the hydroxyl. group a to the triazole base moiety. Those having the D-glycero-configuration in their Fischer projection formula show positive Cotton effect and those with the L-glycero-configuration show negative Cotton effect. This correlation was extended for the assignment of the anomeric configuration of the corresponding glycofuranosyl-C-nucleosides.

引用

页码：283 / 286

页数：4

共 13 条

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