Cisplatin and the sensitive cell

被引：6
作者：
Bagby, GC [1 ]
Olson, SB [1 ]
机构：
[1] Oregon Hlth & Sci Univ, Sch Med, OSHU Canc Inst, Portland, OR 97201 USA
来源：
NATURE MEDICINE | 2003年 / 9卷 / 05期
关键词：
D O I：
10.1038/nm0503-513
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Epigenetic suppression of FANCF, a member of the Fanconi anemia gene family, is now implicated in some ovarian cancers. Might this suppression explain the sensitivity of such cancers to the cross-linking agent cisplatin (pages 568–574)?
引用
收藏
页码：513 / 514
页数：3
相关论文
共 9 条
  • [1] Genetic basis of Fanconi anemia
    Bagby, GC
    [J]. CURRENT OPINION IN HEMATOLOGY, 2003, 10 (01) : 68 - 76
  • [2] The Fanconi anaemia BRCA pathway
    D'Andrea, AD
    Grompe, M
    [J]. NATURE REVIEWS CANCER, 2003, 3 (01) : 23 - 34
  • [3] Biallelic inactivation of BRCA2 in Fanconi anemia
    Howlett, NG
    Taniguchi, T
    Olson, S
    Cox, B
    Waisfisz, Q
    de Die-Smulders, C
    Persky, N
    Grompe, M
    Joenje, H
    Pals, G
    Ikeda, H
    Fox, EA
    D'Andrea, AD
    [J]. SCIENCE, 2002, 297 (5581) : 606 - 609
  • [4] LENSCH MW, IN PRESS BLOOD
  • [5] Interaction of FANCD2 and NBS1 in the DNA damage response
    Nakanishi, K
    Taniguchi, T
    Ranganathan, V
    New, HV
    Moreau, LA
    Stotsky, M
    Mathew, CG
    Kastan, MB
    Weaver, DT
    D'Andrea, AD
    [J]. NATURE CELL BIOLOGY, 2002, 4 (12) : 913 - 920
  • [6] The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC
    Pang, QS
    Christianson, TA
    Keeble, W
    Koretsky, T
    Bagby, GC
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (51) : 49638 - 49643
  • [7] Insights into DNA recombination from the structure of a RAD51-BRCA2 complex
    Pellegrini, L
    Yu, DS
    Lo, T
    Anand, S
    Lee, M
    Blundell, TL
    Venkitaraman, AR
    [J]. NATURE, 2002, 420 (6913) : 287 - 293
  • [8] A novel diagnostic screen for defects in the Fanconi anemia pathway
    Shimamura, A
    Oca, RMC
    Svenson, JL
    Haining, N
    Moreau, LA
    Nathan, DG
    D'Andrea, AD
    [J]. BLOOD, 2002, 100 (13) : 4649 - 4654
  • [9] Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
    Taniguchi, T
    Tischkowitz, M
    Ameziane, N
    Hodgson, SV
    Mathew, CG
    Joenje, H
    Mok, SC
    D'Andrea, AD
    [J]. NATURE MEDICINE, 2003, 9 (05) : 568 - 574
1