Corneal collagen cross-linking to treat infectious keratitis

被引：2

作者：

Atia, R. ^{[1
]}

Jouve, L. ^{[1
]}

Knoeri, J. ^{[1
]}

Georgeon, C. ^{[1
]}

Laroche, L. ^{[1
,2
]}

Borderie, V. ^{[1
,2
]}

Bouheraoua, N. ^{[1
,2
]}

机构：

[1] Ctr Hosp Natl Ophtalmol Quinze Vingts, Serv Ophtalmol 5, 28 Rue Charenton, F-75012 Paris, France

[2] Univ Pierre & Marie Curie Paris VI, Inserm, Inst Vis, UMR S 968, F-75012 Paris, France

来源：

JOURNAL FRANCAIS D OPHTALMOLOGIE | 2018年 / 41卷 / 06期

关键词：

Cornea; Corneal collagen; cross-linking; PACK-CXL; Infectious keratitis; HERPES-SIMPLEX-VIRUS; OPTICAL COHERENCE TOMOGRAPHY; STROMAL FUNGAL KERATITIS; IN-VITRO EFFICACY; A; 365; NM; PHOTOACTIVATED CHROMOPHORE; ANTIBIOTIC-RESISTANCE; ULTRAVIOLET-A; PACK-CXL; PROGRESSIVE KERATOCONUS;

D O I：

10.1016/j.jfo.2017.12.007

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Infectious keratitis area frequent cause of ocular morbidity. Today, new treatments are necessary to combat the emergence of antibiotic resistant germs. Corneal collagen cross-linking has been suggested to treat corneal infectious (PACK-CXL). Its action would be both antimicrobial and protective for the cornea, increasing its biochemical resistence to proteolytic enzymes. In vivo, PACK-CXL might demonstrate good efficacy against bacterial keratitis, contrary to herpetic keratitis for which it is contraindicated. For fungal or amoebic keratitis, results are uncertain regarding its safety and efficacy. The purpose of this paper is to clarify the use of corneal collagen cross-linking to treat infectious keratitis. (C) 2018 Elsevier Masson SAS. All rights reserved.

引用

页码：560 / 568

页数：9

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