Epidemiology of vitamin-D deficiency

被引:7
|
作者
Souberbielle, Jean-Claude [1 ]
机构
[1] Hop Necker Enfants Malad, AP HP, Serv Explorat Fonct, Paris, France
来源
GERIATRIE ET PSYCHOLOGIE NEUROPSYCHIATRIE DE VIEILLISSEMENT | 2016年 / 14卷 / 01期
关键词
vitamin D; vitamin D deficiency; risk factors; general population; osteoporosis; SERUM 25-HYDROXYVITAMIN D; RANDOMIZED-CONTROLLED-TRIALS; PARATHYROID-HORMONE; HYPOVITAMINOSIS D; D SUPPLEMENTATION; D INSUFFICIENCY; HEALTH; ADULTS; WOMEN; RISK;
D O I
10.1684/pnv.2016.0589
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The 25-hydroxyvitamin D (250HD) serum concentration is the consensual marker of vitamin D status. In the general population, the Institute of Medicine considers that a 250HD level >20 ng/mL is sufficient for bone health in most subjects. In osteoporosis patients, in those who have a pathology or who receive drugs that may increase the risk of osteoporosis, as well as in patients with chronic kidney disease, many experts think that an optimal vitamin D status is better defined by a 250HD concentration >30 ng/mL. In the French general population, 43-50% of subjects have a 250HD level <20 ng/mL and approximately 80% have a 250HD <30 ng/mL. In chronic diseased patients, as well as in some categories of the general population such as elderly people, the percentage of subjects with a 250HD level below 20 ng/mL is frequently well above 50%. Epidemiologic studies allow us to identify risk factors for vitamin D deficiency such as ageing, overweight, dark skin pigmentation, wearing covering clothes, or having a low level of outdoor activity. This will help to target vitamin D supplementation to "at-risk" subjects. However, discussions on means to improve the vitamin D status of the overall population such as allowing higher levels of food fortification, are needed.
引用
收藏
页码:7 / 15
页数:9
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