An autopsy case of poisoning with combined trichlorfon (DEP) and phenobarbital: Toxicity of the solvent should also be considered

被引:0
作者
Kinoshita, H. [1 ]
Nishiguchi, M. [1 ]
Kasuda, S. [1 ]
Ouchi, H. [1 ]
Minami, T. [1 ]
Yamamura, T. [1 ]
Matsui, K. [1 ]
Yasui, T. [2 ]
Marukawa, S. [2 ]
Ameno, K. [3 ]
Tsuda, T. [1 ]
Aoki, S. [1 ]
Hiromoto, H. [1 ]
Hishida, S. [1 ]
机构
[1] Hyogo Coll Med, Dept Legal Med, Nishinomiya, Hyogo, Japan
[2] Hyogo Coll Med, Emergency & Crit Care Med, Nishinomiya, Hyogo, Japan
[3] Kagawa Univ, Dept Forens Med, Fac Med, Kagawa, Japan
来源
PROCEEDINGS OF THE XX CONGRESS OF INTERNATIONAL ACADEMY OF LEGAL MEDICINE | 2006年
关键词
D O I
暂无
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
A case of fatal poisoning due to ingestion of trichlorfon (DEP) and phenobarbital is presented. Quantitative toxicological analysis showed the high blood concentrations of DEP, dichlorvos (DDVP; the metabolite of DEP), phenobarbital, methanol (contained as an organic solvent in the commercial products of DEP) and formic acid (the metabolite of methanol). We concluded that the cause of death was due to the combined effects of DEP, phenobarbital and methanol. We should consider the toxicity not only of the main component, but also of the solvents contained in the products.
引用
收藏
页码:27 / +
页数:3
相关论文
共 8 条
  • [1] ACETALDEHYDE, METHANOL, AND ETHANOL ANALYSIS BY HEADSPACE GAS-CHROMATOGRAPHY
    ANTHONY, RM
    SUTHEIMER, CA
    SUNSHINE, I
    [J]. JOURNAL OF ANALYTICAL TOXICOLOGY, 1980, 4 (01) : 43 - 45
  • [2] Arao Tomonori, 2002, Leg Med (Tokyo), V4, P182, DOI 10.1016/S1344-6223(02)00014-7
  • [3] BASELT RC, 2000, DISPOSTION TOXIC DRU
  • [4] Cho Y, 1997, CHEM PHARM BULL, V45, P737, DOI 10.1248/cpb.45.737
  • [5] KUO TL, 1989, JPN J LEGAL MED, V36, P669
  • [6] PREDICTORS OF METHANOL INTOXICATION WITH UNFAVORABLE OUTCOME
    MAHIEU, P
    HASSOUN, A
    LAUWERYS, R
    [J]. HUMAN TOXICOLOGY, 1989, 8 (02): : 135 - 137
  • [7] Miyamoto J., 1959, Botyu-Kagaku Tokyo, V24, P130
  • [8] TOMLIN CDS, 1997, PESTICID MANUAL