In Vitro Studies on the Effect of Sodium Arsenite on Blood Vessels

被引:0
|
作者
Shi, Yuanyuan [1 ]
Chen, Xue [2 ]
Ma, Li [3 ]
机构
[1] Jilin Univ, Hosp 2, Dept Nursing, Changchun 130041, Peoples R China
[2] Jilin Univ, Hosp 2, Dept NICU, Changchun 130033, Peoples R China
[3] Jilin Univ, Hosp 2, Dept Emergency, Changchun 130033, Peoples R China
关键词
arsenic; CAM; toxicity; ANGIOGENESIS; TOXICITY; EXPOSURE; DISEASE; TAIWAN;
D O I
暂无
中图分类号
TE [石油、天然气工业]; TK [能源与动力工程];
学科分类号
0807 ; 0820 ;
摘要
Object: The studies were carried out to explore the effect of sodium arsenite on the angiogenesis to provide theoretical explanation and practical measurement for arsenism. Methods: The angiogenesis of Chorioallantoic membrane (CAM) were used as a model to evaluate in vivo effects of arsenic on it. Results: Arsenic showed a bilateral effect on the angiogenesis in CAM model: the stimulating effect when exposed to low-level and suppressing effects when exposed to high-level arsenic. Conclusion: The mechanism of arsenic vascular toxicity is more complex, which may be studied by further in vivo tests.
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页码:3077 / 3080
页数:4
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