The Role of Fibroblast Activation Protein Ligands in Oncologic PET Imaging

被引：17
|
作者：
Dendl, Katharina [1 ]
Schlittenhardt, Joel [1 ]
Staudinger, Fabian [1 ]
Kratochwil, Clemens [1 ]
Altmann, Anette [1 ,2 ,3 ]
Haberkorn, Uwe [1 ,2 ,3 ]
Giesel, Frederik L. [4 ]
机构：
[1] Univ Hosp Heidelberg, Dept Nucl Med, INF 400, D-69120 Heidelberg, Germany
[2] German Canc Res Ctr, Clin Cooperat Unit Nucl Med, INF280, D-69120 Heidelberg, Germany
[3] German Ctr Lung Res DZL, Translat Lung Res Ctr Heidelberg, D-69120 Heidelberg, Germany
[4] Univ Hosp Dusseldorf, Dept Nucl Med, Dusseldorf, Germany
来源：
PET CLINICS | 2021年 / 16卷 / 03期
关键词：
Fibroblast activation protein; FAP; FAPI PET/CT; Cancer-associated fibroblasts; Small molecule inhibitors; CANCER-ASSOCIATED FIBROBLASTS; DIPEPTIDYL-PEPTIDASE-IV; SERINE-PROTEASE; NEUROPEPTIDE-Y; STROMAL CELLS; EXPRESSION; FAP; SEPRASE; ALPHA; BONE;
D O I：
10.1016/j.cpet.2021.03.012
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
[No abstract available]
引用
收藏
页码：341 / 351
页数：11
相关论文
共 50 条
  • [31] The fibroblast activation protein alpha as a biomarker of pulmonary fibrosis
    Lavis, Philomene
    Garabet, Ani
    Cardozo, Alessandra Kupper
    Bondue, Benjamin
    FRONTIERS IN MEDICINE, 2024, 11
  • [32] The Role of Fibroblast Activation Protein in Glioblastoma and Gliosarcoma: A Comparison of Tissue, 68 Ga-FAPI-46 PET Data, and Survival Data
    Oster, Christoph
    Kessler, Lukas
    Blau, Tobias
    Keyvani, Kathy
    Pabst, Kim M.
    Fendler, Wolfgang P.
    Costa, Pedro Fragoso
    Lazaridis, Lazaros
    Schmidt, Teresa
    Feldheim, Jonas
    Pierscianek, Daniela
    Schildhaus, Hans Ulrich
    Sure, Ulrich
    Ahmadipour, Yahya
    Kleinschnitz, Christoph
    Guberina, Nika
    Stuschke, Martin
    Deuschl, Cornelius
    Scheffler, Bjoeurorn
    Herrmann, Ken
    Kebir, Sied
    Glas, Martin
    JOURNAL OF NUCLEAR MEDICINE, 2024, 65 (08) : 1217 - 1223
  • [33] Fibroblast Activation Protein Overexpression and Clinical Implications in Solid Tumors: A Meta-Analysis
    Liu, Fang
    Qi, Li
    Liu, Bao
    Liu, Jie
    Zhang, Hua
    Che, Dehai
    Cao, JingYan
    Shen, Jing
    Geng, JianXiong
    Bi, Yi
    Ye, LieGuang
    Pan, Bo
    Yu, Yan
    PLOS ONE, 2015, 10 (03):
  • [34] Aged-Related Fibroblast Activation Protein Expression in Skeletal Muscles Evaluated by PET Imaging
    Suh, Minseok
    Gil, Joonhyung
    Kang, Yeon-Koo
    Choi, Hongyoon
    Cheon, Gi Jeong
    JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2025, 16 (01)
  • [35] Development and evaluation of 18F-labeled novel radiopharmaceuticals for PET imaging of fibroblast activation protein expressing tumors
    Zhang, Qingyu
    Hu, Zhoumi
    Zhao, Haitao
    Du, Fuqiang
    Lv, Chun
    Peng, Tukang
    Zhang, Yukai
    Zhang, Bowu
    Liu, Jianjun
    Wang, Cheng
    BIOORGANIC CHEMISTRY, 2025, 160
  • [36] Clinical Findings on Fibroblast Activation Protein in Patients with Gastric Cancer
    Fukumoto, Youji
    Yamada, Yoshinori
    Fukuda, Kenji
    Saito, Hiroaki
    Tatebe, Shigeru
    Tsujitani, Shunichi
    Ikeguchi, Masahide
    YONAGO ACTA MEDICA, 2009, 52 (01) : 21 - 25
  • [37] New Frontiers in Cancer Imaging and Therapy Based on Radiolabeled Fibroblast Activation Protein Inhibitors: A Rational Review and Current Progress
    Imlimthan, Surachet
    Moon, Euy Sung
    Rathke, Hendrik
    Afshar-Oromieh, Ali
    Roesch, Frank
    Rominger, Axel
    Gourni, Eleni
    PHARMACEUTICALS, 2021, 14 (10)
  • [38] Fibroblast activation protein α in tumor microenvironment: Recent progression and implications
    Zi, Fuming
    He, Jingsong
    He, Donghua
    Li, Yi
    Yang, Li
    Cai, Zhen
    MOLECULAR MEDICINE REPORTS, 2015, 11 (05) : 3203 - 3211
  • [39] A specific, transmembrane interface regulates fibroblast activation protein (FAP) homodimerization, trafficking and exopeptidase activity
    Wonganu, Benjamaporn
    Berger, Bryan W.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2016, 1858 (08): : 1876 - 1882
  • [40] Fibroblast activation protein-based theranostics in pancreatic cancer
    Cheng, Chien-shan
    Yang, Pei-wen
    Sun, Yun
    Song, Shao-li
    Chen, Zhen
    FRONTIERS IN ONCOLOGY, 2022, 12
12345