One-pot preparation of hydrophilic citric acid-magnetic nanoparticles for identification of glycopeptides in human saliva

被引：26

作者：

Chu, Huimin ^{[1
,2
]}

Hu, Xufang ^{[1
,2
]}

Yao, Jizong ^{[1
,2
]}

Yan, Guoquan ^{[3
]}

Sun, Nianrong ^{[1
,2
]}

Deng, Chunhui ^{[1
,2
,3
]}

机构：

[1] Fudan Univ, Zhongshan Hosp, Dept Chem, Shanghai 200433, Peoples R China

[2] Fudan Univ, Zhongshan Hosp, Dept Gastroenterol & Hepatol, Shanghai 200433, Peoples R China

[3] Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Inst Biomed Sci, Shanghai 200433, Peoples R China

来源：

TALANTA | 2020年 / 206卷

基金：

中国国家自然科学基金;

关键词：

Glycopeptide enrichment; Human saliva; Magnetic nanoparticles; HILIC; HIGHLY SPECIFIC ENRICHMENT; HIGH-EFFICIENT ENRICHMENT; METAL-ORGANIC FRAMEWORKS; SELECTIVE ENRICHMENT; FACILE SYNTHESIS; GLYCOSYLATION; POLYMER; MECHANISMS; QUANTIFICATION; NANOCOMPOSITES;

D O I：

10.1016/j.talanta.2019.120178

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A facile and mild approach was carried out to synthesize citrate acid-magnetic ferroferric oxide for glycopeptide analysis. The material was synthesized successfully and applied in glycopeptide identification from human saliva, indicating that this method could be a promising tool for glycopeptidome analysis, which also enlightened the simple fabrication of hydrophilic materials in analytical science.

引用

页数：7

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