Gilteritinib significantly prolongs overall survival in patients with FLT3-mutated (FLT3mut+) relapsed/refractory (R/R) acute myeloid leukemia (AML): Results from the Phase III ADMIRAL trial

被引：28

作者：

Perl, Alexander E. ^{[1
]}

Martinelli, Giovanni ^{[2
]}

Cortes, Jorge E. ^{[3
]}

Neubauer, Andreas ^{[4
]}

Berman, Ellin ^{[5
]}

Paolini, Stefania ^{[6
]}

Montesinos, Pau ^{[7
,8
]}

Baer, Maria R. ^{[9
]}

Larson, Richard A. ^{[10
]}

Ustun, Celalettin ^{[11
]}

Fabbiano, Francesco ^{[12
]}

Di Stasi, Antonio ^{[13
]}

Stuart, Robert ^{[14
]}

Olin, Rebecca ^{[15
]}

Kasner, Margaret ^{[16
]}

Ciceri, Fabio ^{[17
]}

Chou, Wen-Chien ^{[18
]}

Podoltsev, Nikolai ^{[19
]}

Recher, Christian ^{[20
]}

Yokoyama, Hisayuki ^{[21
]}

Hosono, Naoko ^{[22
]}

Yoon, Sung-Soo ^{[23
]}

Lee, Je-Hwan ^{[24
]}

Pardee, Timothy ^{[25
]}

Fathi, Amir T. ^{[26
]}

Liu, Chaofeng ^{[27
]}

Liu, Xuan ^{[27
]}

Bahceci, Erkut ^{[27
]}

Levis, Mark J. ^{[28
]}

机构：

[1] Univ Penn, Abramson Canc Ctr, Philadelphia, PA 19104 USA

[2] Ist Sci Romagnolo Studio & Cura Tumori IRST IRCCS, Meldola, Italy

[3] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[4] Univ Klinikum Giessen & Marburg GmbH, Marburg, Germany

[5] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[6] Bologna Univ, L&A Seragnoli Inst Hematol, Sch Med, Bologna, Italy

[7] Hosp Univ & Politecn La Fe, Valencia, Spain

[8] Inst Carlos III, CIBERONC, Madrid, Spain

[9] Univ Maryland, Greenebaum Comprehens Canc Ctr, Baltimore, MD 21201 USA

[10] Univ Chicago, Chicago, IL 60637 USA

[11] Univ Minnesota, Minneapolis, MN USA

[12] Osped Riuniti Villa Sofia Cervello, Palermo, Italy

[13] Univ Alabama Birmingham, Birmingham, AL USA

[14] Med Univ South Carolina, Hollings Canc Ctr, Charleston, SC 29425 USA

[15] Univ Calif San Francisco, San Francisco, CA 94143 USA

[16] Thomas Jefferson Univ, Philadelphia, PA 19107 USA

[17] IRCCS San Raffaele Sci Inst, Milan, Italy

[18] Natl Taiwan Univ, Taipei, Taiwan

[19] Yale Univ, Sch Med, New Haven, CT USA

[20] Inst Univ Canc Toulouse Oncopole, Cedez, France

[21] Natl Hosp Org, Sendai Med Ctr, Sendai, Miyagi, Japan

[22] Univ Fukui, Fukui, Japan

[23] Seoul Natl Univ, Seoul, South Korea

[24] Univ Ulsan, Asan Med Ctr, Coll Med, Seoul, South Korea

[25] Wake Forest Baptist Med Ctr, Winston Salem, NC USA

[26] Harvard Med Sch, Massachusetts Gen Hosp, Boston, MA 02115 USA

[27] Astellas Pharma Global Dev, Northbrook, IL USA

[28] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

来源：

CANCER RESEARCH | 2019年 / 79卷 / 13期

关键词：

D O I：

10.1158/1538-7445.AM2019-CT184

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

CT184

引用

页数：4