Chemical constituents from Saussurea cordifolia

被引:29
作者
Li, Xu-Wen [1 ,2 ]
Guo, Zi-Tao [3 ,4 ]
Zhao, Yun [1 ,2 ]
Zhao, Zheng [3 ,4 ]
Hu, Jin-Feng [1 ,2 ]
机构
[1] E China Normal Univ, Dept Nat Prod Chem Genet Res, Key Lab Brain Funct Genom, Minist Educ, Shanghai 200062, Peoples R China
[2] E China Normal Univ, Shanghai Key Lab Brain Funct Genom MOE & SBFG, Shanghai 200062, Peoples R China
[3] E China Normal Univ, Dept Pharmacol & Toxicol, Key Lab Brain Funct Genom, Minist Educ, Shanghai 200062, Peoples R China
[4] E China Normal Univ, Shanghai Key Lab Brain Funct Genom MOE & SBFG, Shanghai 200062, Peoples R China
关键词
Saussurea cordifolia; Compositae; Acetylenic glycoside; Lignan; MEGASTIGMANE GLUCOSIDES; CELL-LINE; GLYCOSIDES; LEAVES; LIGNAN; ASSAY; MIQ;
D O I
10.1016/j.phytochem.2009.12.016
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Thirty-six naturally occurring compounds, including four C-10-acetylenic glycosides and a lignan, were isolated from the whole plants of Saussurea cordifolia. Their structures were elucidated by means of spectroscopic and chemical methods to be 4,6-decadiyne-1-O-beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranoside (1), 4,6-decadiyne-1-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside (2), (8E)-decaene-4, 6-diyn-1-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside (3), (8Z)-decaene-4,6-diyn-1-O-beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranoside (4), and (2R, 3S, 4S)-4-(4-hydroxy-3-methoxybenzy1)-2-(5-hydroxy-3-methoxypheny1)-3-(hydroxymethyl)-tetrahydrofuran-3-ol (5). (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:682 / 687
页数:6
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