Synthesis and Biological Activity of Organophosphates Phenoxy Derivatives Derived from 2-Mercapto Benzoxazole

被引：1

作者：

Jain, Chandni ^{[1
]}

Choudhary, Neeru ^{[1
]}

Nagar, Meena ^{[1
]}

Seth, Gita ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2014年 / 189卷 / 11期

关键词：

antifungal activity; antibacterial activity; Benzoxazole; phenoxy derivatives; ONE-POT SYNTHESIS; ANTIMICROBIAL ACTIVITY; FUNGICIDAL ACTIVITY; COMPLEXES; LIGANDS; ESTERS;

D O I：

10.1080/10426507.2014.887076

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of biologically active phenoxy derivatives of 2-substituted benzoxazole organophosphates have been synthesized by the reaction of S-(benzoxazolyl-2)phosphorodichloridothioate/phosphorodichloridodithioate with phenol/4-chlorophenol/4-nitrophenol in 1:1 and 1:2 molar ratio. These compounds have been characterized by elemental analysis, IR, H-1 NMR, and P-31 NMR spectral studies. The antibacterial activity of these 2-substituted benzoxazolephenoxy derivatives has been evaluated against pathogenic bacteria Staphylococcus aureus (+ve) and Escherichia coli (-ve). The antifungal activity of these 2-substituted benzoxazolephenoxy derivatives has been evaluated against pathogenic fungi Aspergillusniger and Fusariumoxysporium. All the compounds were found to have moderate antibacterial and antifungal activity.

引用

页码：1699 / 1705

页数：7

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