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Synthesis and evaluation of quinoline carboxyguanidines as antidiabetic agents
被引:146
作者
:
Edmont, D
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
Edmont, D
[
1
]
Rocher, R
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
Rocher, R
[
1
]
Plisson, C
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
Plisson, C
[
1
]
Chenault, J
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
Chenault, J
[
1
]
机构
:
[1]
Univ Orleans, Inst Chim Organ & Analyt, F-45067 Orleans 2, France
来源
:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
|
2000年
/ 10卷
/ 16期
关键词
:
D O I
:
10.1016/S0960-894X(00)00354-1
中图分类号
:
R914 [药物化学];
学科分类号
:
100701 ;
摘要
:
The synthesis and in vivo activities of a series of substituted quinoline carboxyguanidines as a possible novel class of antidiabetic agents is described. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1831 / 1834
页数:4
相关论文
共 7 条
[1]
Studies on pyrazinoylguanidine .1. Characterization of metabolic effects in diabetic rats
[J].
ARahim, YI
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0
h-index:
0
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PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
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PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
Beyer, KH
;
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引用数:
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PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
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.
PHARMACOLOGY,
1996,
52
(03)
:135
-144
[2]
IRREVERSIBLE ENZYME-INHIBITORS .190. INHIBITION OF SOME DEHYDROGENASES BY 1-SUBSTITUTED-1,4-DIHYDRO-4-QUINOLONE-3-CARBOXYLIC ACIDS
[J].
BAKER, BR
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0
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0
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0
BAKER, BR
;
BRAMHALL, RR
论文数:
0
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0
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BRAMHALL, RR
.
JOURNAL OF MEDICINAL CHEMISTRY,
1972,
15
(03)
:233
-&
[3]
1H-PYRAZOLE-1-CARBOXAMIDINE HYDROCHLORIDE - AN ATTRACTIVE REAGENT FOR GUANYLATION OF AMINES AND ITS APPLICATION TO PEPTIDE-SYNTHESIS
[J].
BERNATOWICZ, MS
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0
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Department of Macromolecular Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, New Jersey 08543, Princeton
BERNATOWICZ, MS
;
WU, YL
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0
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Department of Macromolecular Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, New Jersey 08543, Princeton
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;
MATSUEDA, GR
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引用数:
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h-index:
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Department of Macromolecular Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, New Jersey 08543, Princeton
MATSUEDA, GR
.
JOURNAL OF ORGANIC CHEMISTRY,
1992,
57
(08)
:2497
-2502
[4]
SYNTHESIS OF 1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID-DERIVATIVES AS INHIBITORS OF RAT LENS ALDOSE REDUCTASE
[J].
BUYUKBINGOL, E
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0
引用数:
0
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0
机构:
ANKARA UNIV,FAC PHARM,DEPT BIOCHEM,ANKARA,TURKEY
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ARCHIV DER PHARMAZIE,
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327
(03)
:129
-131
[5]
ORGANIC AZIDES IN HETEROCYCLIC SYNTHESIS .17. SYNTHESIS AND REACTIONS OF TETRAZOLO[1,5-A]PYRIMIDINES
[J].
KAPPE, T
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0
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0
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UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
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UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
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;
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UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
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Increase in insulin release from rat pancreatic islets by quinolone antibiotics
[J].
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1996,
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(02)
:372
-376
[7]
Yamamoto T, 1997, CHEM PHARM BULL, V45, P1282
←
1
→
共 7 条
[1]
Studies on pyrazinoylguanidine .1. Characterization of metabolic effects in diabetic rats
[J].
ARahim, YI
论文数:
0
引用数:
0
h-index:
0
机构:
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
ARahim, YI
;
Beyer, KH
论文数:
0
引用数:
0
h-index:
0
机构:
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
Beyer, KH
;
Vesell, ES
论文数:
0
引用数:
0
h-index:
0
机构:
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
PENN STATE UNIV, COLL MED, DEPT PHARMACOL, HERSHEY, PA 17033 USA
Vesell, ES
.
PHARMACOLOGY,
1996,
52
(03)
:135
-144
[2]
IRREVERSIBLE ENZYME-INHIBITORS .190. INHIBITION OF SOME DEHYDROGENASES BY 1-SUBSTITUTED-1,4-DIHYDRO-4-QUINOLONE-3-CARBOXYLIC ACIDS
[J].
BAKER, BR
论文数:
0
引用数:
0
h-index:
0
BAKER, BR
;
BRAMHALL, RR
论文数:
0
引用数:
0
h-index:
0
BRAMHALL, RR
.
JOURNAL OF MEDICINAL CHEMISTRY,
1972,
15
(03)
:233
-&
[3]
1H-PYRAZOLE-1-CARBOXAMIDINE HYDROCHLORIDE - AN ATTRACTIVE REAGENT FOR GUANYLATION OF AMINES AND ITS APPLICATION TO PEPTIDE-SYNTHESIS
[J].
BERNATOWICZ, MS
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Macromolecular Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, New Jersey 08543, Princeton
BERNATOWICZ, MS
;
WU, YL
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Macromolecular Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, New Jersey 08543, Princeton
WU, YL
;
MATSUEDA, GR
论文数:
0
引用数:
0
h-index:
0
机构:
Department of Macromolecular Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, New Jersey 08543, Princeton
MATSUEDA, GR
.
JOURNAL OF ORGANIC CHEMISTRY,
1992,
57
(08)
:2497
-2502
[4]
SYNTHESIS OF 1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID-DERIVATIVES AS INHIBITORS OF RAT LENS ALDOSE REDUCTASE
[J].
BUYUKBINGOL, E
论文数:
0
引用数:
0
h-index:
0
机构:
ANKARA UNIV,FAC PHARM,DEPT BIOCHEM,ANKARA,TURKEY
BUYUKBINGOL, E
;
DAS, N
论文数:
0
引用数:
0
h-index:
0
机构:
ANKARA UNIV,FAC PHARM,DEPT BIOCHEM,ANKARA,TURKEY
DAS, N
;
KLOPMAN, G
论文数:
0
引用数:
0
h-index:
0
机构:
ANKARA UNIV,FAC PHARM,DEPT BIOCHEM,ANKARA,TURKEY
KLOPMAN, G
.
ARCHIV DER PHARMAZIE,
1994,
327
(03)
:129
-131
[5]
ORGANIC AZIDES IN HETEROCYCLIC SYNTHESIS .17. SYNTHESIS AND REACTIONS OF TETRAZOLO[1,5-A]PYRIMIDINES
[J].
KAPPE, T
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
KAPPE, T
;
ROSCHGER, P
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
ROSCHGER, P
;
FARBER, G
论文数:
0
引用数:
0
h-index:
0
机构:
UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
UNIV GRAZ,INST PHYS CHEM,A-8010 GRAZ,AUSTRIA
FARBER, G
.
JOURNAL OF HETEROCYCLIC CHEMISTRY,
1993,
30
(05)
:1267
-1271
[6]
Increase in insulin release from rat pancreatic islets by quinolone antibiotics
[J].
Maeda, N
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Maeda, N
;
Tamagawa, T
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Tamagawa, T
;
Niki, I
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Niki, I
;
Miura, H
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Miura, H
;
Ozawa, K
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Ozawa, K
;
Watanabe, G
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Watanabe, G
;
Nonogaki, K
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Nonogaki, K
;
Uemura, K
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Uemura, K
;
Iguchi, A
论文数:
0
引用数:
0
h-index:
0
机构:
NAGOYA UNIV,SCH MED,DEPT INTERNAL MED 3,SHOWA KU,NAGOYA,AICHI 466,JAPAN
Iguchi, A
.
BRITISH JOURNAL OF PHARMACOLOGY,
1996,
117
(02)
:372
-376
[7]
Yamamoto T, 1997, CHEM PHARM BULL, V45, P1282
←
1
→