INDUCED PLURIPOTENT STEM CELLS - HOPES, FEARS AND VISIONS

被引：0
作者：
Archacka, Karolina [1 ]
Grabowska, Iwona [1 ]
Ciemerych, Maria A. [1 ]
机构：
[1] Uniwersytet Warszawski, Wydzial Biol, Inst Zool, Zaklad Cytol, PL-02096 Warsaw, Poland
来源：
POSTEPY BIOLOGII KOMORKI | 2010年 / 37卷 / 01期
关键词：
ES cells; iPS cells; pluripotency; Oct3/4; Sox2; Klf4; c-Myc; differentiation; HUMAN SOMATIC-CELLS; IPS CELLS; DIRECTED DIFFERENTIATION; TUMOR-SUPPRESSOR; GENERATION; MOUSE; FIBROBLASTS; EFFICIENT; DISEASE; SYSTEM;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In 2006 first paper describing reprogramming of fibroblast into pluripotent Cell. i.e. one that is able to differentiate into all tissues was published Before that spectacular achievement many projects devoted to study the mechanisms of cell de-differentiation led to the establishment of animal cloning techniques and also derivation of embryonic stem cell lines. Present review summarizes the history of these studies and also describes pioneer works leading to derivation of induced pluripotent stem cells, current methods of reprogramming. and possible applications of these cells
引用
收藏
页码：41 / 62
页数：22
相关论文
共 102 条
  • [1] Generation of pluripotent stem cells from adult mouse liver and stomach cells
    Aoi, Takashi
    Yae, Kojiro
    Nakagawa, Masato
    Ichisaka, Tomoko
    Okita, Keisuke
    Takahashi, Kazutoshi
    Chiba, Tsutomu
    Yamanaka, Shinya
    [J]. SCIENCE, 2008, 321 (5889) : 699 - 702
  • [2] Adult mice generated from induced pluripotent stem cells
    Boland, Michael J.
    Hazen, Jennifer L.
    Nazor, Kristopher L.
    Rodriguez, Alberto R.
    Gifford, Wesley
    Martin, Greg
    Kupriyanov, Sergey
    Baldwin, Kristin K.
    [J]. NATURE, 2009, 461 (7260) : 91 - U94
  • [3] Core transcriptional regulatory circuitry in human embryonic stem cells
    Boyer, LA
    Lee, TI
    Cole, MF
    Johnstone, SE
    Levine, SS
    Zucker, JR
    Guenther, MG
    Kumar, RM
    Murray, HL
    Jenner, RG
    Gifford, DK
    Melton, DA
    Jaenisch, R
    Young, RA
    [J]. CELL, 2005, 122 (06) : 947 - 956
  • [4] Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells
    Brambrink, Tobias
    Foreman, Ruth
    Welstead, G. Grant
    Lengner, Christopher J.
    Wernig, Marius
    Suh, Heikyung
    Jaenisch, Rudolf
    [J]. CELL STEM CELL, 2008, 2 (02) : 151 - 159
  • [5] KLF4 and PBX1 Directly Regulate NANOG Expression in Human Embryonic Stem Cells
    Chan, Ken Kwok-Keung
    Zhang, Jingyao
    Chia, Na-Yu
    Chan, Yun-Shen
    Sim, Hui Shan
    Tan, Ker Sin
    Oh, Steve Kah-Weng
    Ng, Huck-Hui
    Choo, Andre Boon-Hwa
    [J]. STEM CELLS, 2009, 27 (09) : 2114 - 2125
  • [6] Ciemerych MA, 2008, POSTEPY BIOL KOMORKI, V35, P183
  • [7] Di Berardino MA, 2006, METH MOL B, V348, P3
  • [8] Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    Dimos, John T.
    Rodolfa, Kit T.
    Niakan, Kathy K.
    Weisenthal, Laurin M.
    Mitsumoto, Hiroshi
    Chung, Wendy
    Croft, Gist F.
    Saphier, Genevieve
    Leibel, Rudy
    Goland, Robin
    Wichterle, Hynek
    Henderson, Christopher E.
    Eggan, Kevin
    [J]. SCIENCE, 2008, 321 (5893) : 1218 - 1221
  • [9] Induced pluripotent stem cells from a spinal muscular atrophy patient
    Ebert, Allison D.
    Yu, Junying
    Rose, Ferrill F., Jr.
    Mattis, Virginia B.
    Lorson, Christian L.
    Thomson, James A.
    Svendsen, Clive N.
    [J]. NATURE, 2009, 457 (7227) : 277 - U1
  • [10] Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression
    Eminli, Sarah
    Utikal, Jochen
    Arnold, Katrin
    Jaenisch, Rudolf
    Hochedlinger, Konrad
    [J]. STEM CELLS, 2008, 26 (10) : 2467 - 2474
12345678910