Acute facial nerve palsy in children in a Lyme disease-endemic area in the Netherlands

被引：8

作者：

Bruinsma, R. A. ^{[1
,2
]}

Smulders, C. A. ^{[3
]}

Vermeeren, Y. M. ^{[1
,4
]}

van Kooten, B. ^{[1
,5
]}

Cats, E. A. ^{[2
,5
]}

van Hees, B. ^{[1
,6
]}

van Hensbroek, M. Boele ^{[7
]}

Hovius, J. W. ^{[8
]}

Zomer, T. P. ^{[1
]}

机构：

[1] Gelre Hosp, Lyme Ctr Apeldoorn, Apeldoorn, Netherlands

[2] Gelre Hosp, Dept Pediat, Apeldoorn, Netherlands

[3] Univ Med Ctr Utrecht, Dept Pediat, Utrecht, Netherlands

[4] Gelre Hosp, Dept Internal Med, Apeldoorn, Netherlands

[5] Gelre Hosp, Dept Neurol, Apeldoorn, Netherlands

[6] Gelre Hosp, Dept Med Microbiol & Infect Prevent, Apeldoorn, Netherlands

[7] Univ Amsterdam, Amsterdam Med Ctr, Dept Pediat, Amsterdam, Netherlands

[8] Univ Amsterdam, Amsterdam Med Ctr, Amsterdam Multidisciplinary Lyme Borreliosis Ctr, Amsterdam, Netherlands

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2021年 / 40卷 / 11期

关键词：

Lyme neuroborreliosis; Facial nerve palsy; Borrelia; Lyme disease; Children; CEREBROSPINAL-FLUID; DIAGNOSIS; NEUROBORRELIOSIS; CXCL13;

D O I：

10.1007/s10096-021-04273-8

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We assessed the prevalence of Lyme neuroborreliosis in children with acute facial nerve palsy in a Lyme-endemic region and patient characteristics associated with this. All children visiting one of three participating hospitals between January 2010 and December 2016 were included in the study. Of 104 children referred to the hospital with facial nerve palsy, 43% had Lyme neuroborreliosis and 57% idiopathic facial palsy. Characteristics significantly associated with Lyme neuroborreliosis were headache (55% versus 18%), meningeal irritation (21% versus 5%), presentation in summer months (69% versus 37%), and a previous tick bite (33% versus 7%).

引用

页码：2455 / 2458

页数：4

共 18 条

[1] Diagnosis of Lyme borreliosis [J].

Aguero-Rosenfeld, ME ;

Wang, GQ ;

Schwartz, I ;

Wormser, GP .

CLINICAL MICROBIOLOGY REVIEWS, 2005, 18 (03) :484-+

[2] Humoral Immune Responses in Patients with Lyme Neuroborreliosis [J].

Cerar, Tjasa ;

Ogrinc, Katarina ;

Strle, Franc ;

Ruzic-Sabljic, Eva .

CLINICAL AND VACCINE IMMUNOLOGY, 2010, 17 (04) :645-650

[3]

CHRISTEN HJ, 1990, ACTA PAEDIATR SCAND, V79, P1219

[4]

Dutch Quality Institute for Health Care (CBO), 2013, DUTCH GUID LYM DIS

[5] Lyme disease in children [J].

Feder, Henry M., Jr. .

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2008, 22 (02) :315-+

[6] CXCL13 and neopterin concentrations in cerebrospinal fluid of patients with Lyme neuroborreliosis and other diseases that cause neuroinflammation [J].

Hytonen, Jukka ;

Kortela, Elisa ;

Waris, Matti ;

Puustinen, Juha ;

Salo, Jemiina ;

Oksi, Jarmo .

JOURNAL OF NEUROINFLAMMATION, 2014, 11

[7] Facial palsy: Etiology, outcome and management in children [J].

Jenke, Andreas Christoph ;

Stoek, Lisa-Marie ;

Zilbauer, Matthias ;

Wirth, Stefan ;

Borusiak, Peter .

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2011, 15 (03) :209-213

[8] The predictive value of CXCL13 in suspected Lyme neuroborreliosis: a retrospective cross-sectional study [J].

Knudtzen, Fredrikke Christie ;

Nilsson, Anna Christine ;

Hovius, Joppe W. ;

Skarphedinsson, Sigurdur .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2020, 39 (08) :1461-1470

[9] Borrelia burgdorferi VlsE antigen for the serological diagnosis of Lyme borreliosis [J].

Marangoni, A. ;

Moroni, A. ;

Accardo, S. ;

Cevenini, R. .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2008, 27 (05) :349-354

[10]

Mikrogen Diagnostik, RECOMLINE BORR INSTR

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