Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients

被引：4
作者：
Potratz, Jenny C. [1 ]
Guddorf, Sarah [1 ]
Ahlmann, Martina [2 ]
Tekaat, Maria [1 ]
Rossig, Claudia [2 ]
Omran, Heymut [1 ]
Masjosthusmann, Katja [1 ]
Groll, Andreas H. [2 ]
机构：
[1] Univ Childrens Hosp Munster, Dept Gen Pediat, Munster, Germany
[2] Univ Childrens Hosp Munster, Dept Pediat Hematol & Oncol, Munster, Germany
来源：
FRONTIERS IN ONCOLOGY | 2021年 / 11卷
关键词：
extracorporeal membrane oxygenation; leukemia; cancer; transplantation; immunosuppression; children; respiratory failure; infection;
D O I：
10.3389/fonc.2021.664928
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for severe respiratory and/or circulatory failure. Few data exist on the potential benefit of ECMO in immunocompromised pediatric patients with cancer and/or hematopoietic cell transplantation (HCT). Over a period of 12 years, eleven (1.9%) of 572 patients with new diagnosis of leukemia/lymphoma and nine (3.5%) of 257 patients post allogeneic HCT underwent ECMO at our center. Five (45%) and two (22%) patients, respectively, survived to hospital discharge with a median event-free survival of 4.2 years. Experiences and outcomes in this cohort may aid clinicians and families when considering ECMO for individual patients.
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页数：7
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