Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients

被引：4

作者：

Potratz, Jenny C. ^{[1
]}

Guddorf, Sarah ^{[1
]}

Ahlmann, Martina ^{[2
]}

Tekaat, Maria ^{[1
]}

Rossig, Claudia ^{[2
]}

Omran, Heymut ^{[1
]}

Masjosthusmann, Katja ^{[1
]}

Groll, Andreas H. ^{[2
]}

机构：

[1] Univ Childrens Hosp Munster, Dept Gen Pediat, Munster, Germany

[2] Univ Childrens Hosp Munster, Dept Pediat Hematol & Oncol, Munster, Germany

来源：

FRONTIERS IN ONCOLOGY | 2021年 / 11卷

关键词：

extracorporeal membrane oxygenation; leukemia; cancer; transplantation; immunosuppression; children; respiratory failure; infection;

D O I：

10.3389/fonc.2021.664928

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for severe respiratory and/or circulatory failure. Few data exist on the potential benefit of ECMO in immunocompromised pediatric patients with cancer and/or hematopoietic cell transplantation (HCT). Over a period of 12 years, eleven (1.9%) of 572 patients with new diagnosis of leukemia/lymphoma and nine (3.5%) of 257 patients post allogeneic HCT underwent ECMO at our center. Five (45%) and two (22%) patients, respectively, survived to hospital discharge with a median event-free survival of 4.2 years. Experiences and outcomes in this cohort may aid clinicians and families when considering ECMO for individual patients.

引用

页数：7

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