Molecular characterization of SAT 2 foot-and-mouth disease virus from post-outbreak slaughtered animals: implications for disease control in Uganda

被引：17

作者：

Balinda, S. N. ^{[1
]}

Belsham, G. J. ^{[2
]}

Masembe, C. ^{[1
]}

Sangula, A. K. ^{[1
]}

Siegismund, H. R. ^{[3
]}

Muwanika, V. B. ^{[1
]}

机构：

[1] Makerere Univ, Inst Environm & Nat Resources, Mol Biol Lab, Kampala, Uganda

[2] Tech Univ Denmark, Natl Vet Inst, Lindhohn, Kalvehave, Denmark

[3] Univ Copenhagen, Dept Biol, Copenhagen, Denmark

来源：

EPIDEMIOLOGY AND INFECTION | 2010年 / 138卷 / 08期

关键词：

FMD control; SAT; 2; sequence divergence; TRANSMISSION;

D O I：

10.1017/S0950268809991427

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In Uganda, limiting the extent of foot-and-mouth disease (FMD) spread during outbreaks involves short-term measures such as ring vaccination and restrictions of the movement of livestock and their products to and from the affected areas. In this study, the presence of FMD virus RNA was investigated in cattle samples 3 months after FMD quarantine measures had been lifted following an outbreak in 2004. Oropharyngeal tissue samples were obtained from 12 cattle slaughtered in a small town abattoir in Kiboga. FMD virus RNA was detected by diagnostic RT-PCR in nine of the 12 tissue samples. Part of the coding region for the capsid protein VP1 was amplified and sequenced. All samples were identified as belonging to the SAT 2 serotype. The implications for FMD control of both virus introduction into Uganda and the presence of carrier animals following outbreaks are discussed.

引用

页码：1204 / 1210

页数：7

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