A PURIFIED EXTRACT FROM BROWN TRUFFLES OF THE SPECIES TERFEZIA CLAVERYI CHATIN AND ITS ANTIMICROBIAL ACTIVITY

被引：0

作者：

Casarica, Angela ^{[1
]}

Moscovici, Misu ^{[1
]}

Daas, Marwan ^{[2
]}

Nicu, Ioana ^{[3
]}

Panteli, Minerva ^{[3
]}

Rasit, Iuksel ^{[3
]}

机构：

[1] Natl Inst Chem Pharmaceut Res & Dev ICCF, Dept Pharmaceut Biotechnol, 112 Vitan Ave, Bucharest 031299, Romania

[2] Univ Paris 05, Fac Med Dent, Dept Dent Surg, 5 Rue Garanciere, F-75006 Paris, France

[3] Natl Inst Chem Pharmaceut Res & Dev ICCF, Dept Pharmacol, 112 Vitan Ave, Bucharest 031299, Romania

来源：

FARMACIA | 2016年 / 64卷 / 02期

关键词：

Terfezia claveryi Chatin; brown truffles extract; antimicrobial activity; GENTAMICIN; THERAPY;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A purified aqueous extract of Terfezia claveryi Chatin brown truffles was obtained by water extraction, concentration and purification by ultrafiltration. The concentrated extract was tested for antimicrobial activity against three microorganisms: a Gram-negative bacterium (Escherichia coli ATCC 8739) and two Gram-positive bacteria (Staphylococcus aureus ATCC 6538P and Staphylococcus epidermidis ATCC 12228), using the agar diffusion method and it presented a very good activity in all three cases, with growth inhibition zones of 20.5 mm, 21 mm and 26.5 mm respectively. The brown truffle extract showed an antimicrobial activity comparable with that of 300 - 400 mu g/mL and 25 mu g/mL gentamicin sulphate chosen as reference, respectively.

引用

页码：298 / 301

页数：4

共 26 条

[1]

Al-Naama M. M., 1988, Iraqi Journal of Agricultural Sciences, 'ZANCO', V6, P51

[2] CONCENTRATION OF GENTAMICIN IN EXPERIMENTAL CORNEAL ULCERS - TOPICAL VS SUBCONJUNCTIVAL THERAPY [J].

BAUM, JL ;

BARZA, M ;

SHUSHAN, D ;

WEINSTEIN, L .

ARCHIVES OF OPHTHALMOLOGY, 1974, 92 (04) :315-317

[3] Anti-infective drug therapy in ophthalmology - Part 1: Bacterial infections [J].

Behrens-Baumann, W .

KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 2004, 221 (07) :539-545

[4]

Blodi F.C., 1988, DIFFERENTIAL DIAGNOS, P84

[5]

Bokhary H. A., 1993, Journal of Food Composition and Analysis, V6, P285, DOI 10.1006/jfca.1993.1031

[6] THE FATTY-ACID COMPONENTS OF THE DESERT TRUFFLE AL KAMAH OF SAUDI-ARABIA [J].

BOKHARY, HA ;

SULEIMAN, AAA ;

BASALAH, MO .

JOURNAL OF FOOD PROTECTION, 1989, 52 (09) :668-669

[7] CHEMICAL-COMPOSITION OF DESERT TRUFFLES FROM SAUDI-ARABIA [J].

BOKHARY, HA ;

SULEIMAN, AAA ;

BASALAH, MO ;

PARVEZ, S .

CANADIAN INSTITUTE OF FOOD SCIENCE AND TECHNOLOGY JOURNAL-JOURNAL DE L INSTITUT CANADIEN DE SCIENCE ET TECHNOLOGIE ALIMENTAIRES, 1987, 20 (05) :336-341

[8] Pseudomembranous conjunctivitis following topical gentamicin therapy [J].

Bullard, SR ;

ODay, DM .

ARCHIVES OF OPHTHALMOLOGY, 1997, 115 (12) :1591-1592

[9]

Denniston A.K.O., 2009, OXFORD HDB OPHTHALMO, P91

[10] Emerging fluoroquinolone resistance in bacterial keratitis - A 5-year review [J].

Goldstein, MH ;

Kowalski, RP ;

Gordon, YJ .

OPHTHALMOLOGY, 1999, 106 (07) :1313-1318

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