Simulating PIP2-induced gating transitions in Kir6.2 channels

被引：0
|
作者：
Bruendl, Michael [1 ]
Pellikan, Sarala [1 ]
Stary-Weinzinger, Anna [1 ]
机构：
[1] Univ Vienna, Vienna, Austria
来源：
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS | 2021年 / 50卷 / SUPPL 1期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
P-314
引用
收藏
页码：180 / 180
页数：1
相关论文
共 50 条
  • [21] Kir6.2 Channel Gating by Intracellular Protons: Subunit Stoichiometry for Ligand Binding and Channel Gating
    Runping Wang
    Junda Su
    Xiaoli Zhang
    Yun Shi
    Ningren Cui
    Vivian A. Onyebuchi
    Chun Jiang
    The Journal of Membrane Biology, 2006, 213 : 155 - 164
  • [22] An Intramolecular Interaction Controls a Rate-Limiting Step in ATP-Dependent Gating of Kir6.2 Channels
    Zhang, Roger S.
    Wright, Jordan
    Pless, Stephan A.
    Nunez, John-Jose
    Kim, Robin Y.
    Yang, Runying
    Ahern, Christopher A.
    Kurata, Harley T.
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 541A - 542A
  • [23] Critical membrane helical domains and amino acid residues in gating Kir6.2 channels by intracellular ATP.
    Wu, JP
    Piao, HL
    Jiang, C
    BIOPHYSICAL JOURNAL, 2003, 84 (02) : 81A - 81A
  • [24] Rescue and Gating of a Disease Mutation at an M2 glycine in Kir6.2 of ATP-Sensitive Potassium (KATP) Channels
    Bushman, Jeremy D.
    Tewson, Paul H.
    Shyng, Show-Ling
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 465A - 466A
  • [25] Kir6.2 channel gating by intracellular protons: Subunit stoichiometry for ligand binding and channel gating
    Wang, Runping
    Su, Junda
    Zhang, Xiaoli
    Shi, Yun
    Cui, Ningren
    Onyebuchi, Vivian A.
    Jiang, Chun
    JOURNAL OF MEMBRANE BIOLOGY, 2006, 213 (03): : 155 - 164
  • [26] A gating mutation at the internal mouth of the Kir6.2 pore is associated with DEND syndrome
    Proks, P
    Girard, C
    Haider, S
    Gloyn, AL
    Hattersley, AT
    Sansom, MSP
    Ashcroft, FM
    EMBO REPORTS, 2005, 6 (05) : 470 - 475
  • [27] Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism
    Shimomura, Kenju
    Flanagan, Sarah E.
    Zadek, Brittany
    Lethby, Mark
    Zubcevic, Lejla
    Girard, Christophe A. J.
    Petz, Oliver
    Mannikko, Roope
    Kapoor, Ritika R.
    Hussain, Khalid
    Skae, Mars
    Clayton, Peter
    Hattersley, Andrew
    Ellard, Sian
    Ashcroft, Frances M.
    EMBO MOLECULAR MEDICINE, 2009, 1 (03) : 166 - 177
  • [28] The antiarrhythmic agent cibenzoline inhibits KATP channels by binding to Kir6.2
    Mukai, E
    Ishida, H
    Horie, M
    Noma, A
    Seino, Y
    Takano, M
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 251 (02) : 477 - 481
  • [29] Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: A mechanistic study
    Proks, Peter
    de Wet, Heidi
    Ashcroft, Frances M.
    JOURNAL OF GENERAL PHYSIOLOGY, 2014, 144 (05): : 469 - 486
  • [30] Ligand-induced closure of inward rectifier Kir6.2 channels traps spermine in the pore
    Phillips, LR
    Nichols, CG
    JOURNAL OF GENERAL PHYSIOLOGY, 2003, 122 (06): : 795 - 804
12345